Dr. NTR University of Health Sciences Bachelor of Medicine and Bachelor of Surgery 2nd Year Microbiology Previous Year Question Papers

1.

Atherosclerosis of coronary arteries is associated with infection by a. Chlamydiae pneumina b. Legionella pneumophila c. Mycoplasma pneumoniae d. D Klebsiella pneumoniae

1 Mark

2.

Example of Gram positive bacilli arranged in chains with a bamboo stick appearance a. Actinomyces israelii b. Bacillus anthracis c. Nocardia asteroids d. Corynebacterium diphtheria

1 Mark

3.

Malignant otitis externa in elderly diabetic patients is caused by a. Burkholderia pseudomallei b. Pseudomonas aeruginosa c. Acinetobacter baumannii d. Stenotrophomonas maltophila

1 Mark

4.

One of the following is a transport medium a. Lowenstein Jensen medium b. Thiosulfate citrate bile salt sucrose agar medium c. Cary Blair medium d. Potassium tellurite agar medium

1 Mark

5.

The composition of Trivalent influenza vaccine does not include a. A/HIN1 strain b. A/H3N2 strain c. A/HSN1 strain d. Influenza B strain

1 Mark

6.

Indole negative is a. Escherichia coli b. Klebsiella pneumoniae c. Proteus vulgaris d. Vibrio cholerae

1 Mark

7.

Antibody that crosses placenta is a. IgG b. IgA c. IgM d. IgD

1 Mark

8.

Rajesh, a 28 year old male, was admitted to the hospital with complaints of low grade fever, loss of weight and appetite and chronic cough with expectoration for past 6 months. Sputum examination revealed long, slender and beaded acid fast bacilli a. What is your provisional diagnosis b. Describe the pathogenesis of the condition c. Describe the lab diagnosis in detail and briefly mention about drug resistance

15 Marks

9.

Describe the morphology, pathogenesis and laboratory diagnosis of Echinococcus granulosis

15 Marks

10.

Describe the pathogenesis, lab diagnosis and prophylaxis of poliomyelitis

15 Marks

11.

A 10-year-old boy presents to outpatient department with history of fever of 5 days duration. The mother says the boy has been having fever everyday and the fever does not touch the baseline. She also adds that he has been presenting with rashes on the abdomen. On examination the doctor observes that the boy is toxic with the fever of 102 deg and that spleen is palpable on examination with the coating of the tongue a. What is the clinical diagnosis and what is the probable etiology b. Describe the pathogenesis and lab diagnosis c. Mention the prophylaxis and prevention

15 Marks

12.

Primary amoebic encephalitis

5 Marks

13.

Laboratory diagnosis of kala-azar

5 Marks

14.

Lab diagnosis of urinary tract infections

5 Marks

15.

Diarrheagenic E. coil

5 Marks

16.

Cutaneous anthrax

5 Marks

17.

Methods of HIV detection in laboratory settings

5 Marks

18.

Lab diagnosis of syphilis

5 Marks

19.

Gaseous disinfectants

5 Marks

20.

Atypical pneumonia

5 Marks

21.

Alternative complement pathway

5 Marks

22.

Diagnosis and prophylaxis of HINI infection Saint

5 Marks

23.

Larva Migrans

5 Marks

24.

Oncogenic viruses

5 Marks

25.

An eight year old child presents with the history of fever followed by distension of abdomen as observed by her mother USG report showed massive splenomegaly and bone marrow biopsy was done. The result came as leukemia. How do you inform the reports to their parents from doctor point of view

5 Marks

26.

Viral hemorrhagic fevers

5 Marks

27.

24 old college girl had a bakery items from the bakery. After consuming food she had vomiting with in 6 hours of consumption associated with abdominal pain. What could have been the probable etiology. Elaborate it pathogenesis and tab diagnosis

5 Marks

28.

25 year old man comes to blood bank for blood donation. On collecting the sample for testing he was found to be hepatitis B positive. How ill you disclose the result to the patient

5 Marks

29.

Mycetoma

5 Marks

30.

19 year old lady comes to gynecology department with history of thin green colour foul smelling discharge from the vagina associated with intense pruritis a. What is the causative organisms b. Discuss the pathogenesis and lab diagnosis

5 Marks

31.

Describe the pathogenesis and lab diagnosis of bacillary dysentery

5 Marks

32.

A 20 year old female college student presents with fever, sore throat and cervical lymphadenopathy. Paul Bunnel test was positive and peripheral blood examination reveals atypical lymphocytes. The presentation is most likely caused by a. Cytomegalovirus b. Epstein-Barr virus c. Adeno virus d. Rhino virus

1 Mark

33.

Toxigenicity to Corynebacterium diphtheria is imparted by a. Transformation b. Conjugation c. Transduction d. Transposition

1 Mark

34.

The drug of choice for pneumonia caused by Pneumocytosis jirovecii is a. Cotrimoxazole b. Amphotericin B c. Itraconazole d. Flucytosine

1 Mark

35.

CSF analysis reveals elevated leukocyte count with predominant neutrophils, decreased glucose levels and increased protein levels. The presentation most like refers to a. Normal CSF analysis b. Pyogenic meningitis c. Viral meningitis d. Tuberculous meningitis

1 Mark

36.

Example of Precipitation reaction is a. Widal test b. VDRL test c. Weil Felix reaction d. Paul Bunnel test

1 Mark

37.

The etiological agent of Hand foot and mouth disease is a. Coxsackie virus b. Polio virus c. Herpes simplex virus d. Enterovirus 72

1 Mark

38.

Asthma is a manifestation of a. Type I hypersensitivity reaction b. Type II hypersensitivity reaction c. Type III hypersensitivity reaction d. Type IV hypersensitivity reaction

1 Mark

39.

One of the following Arboviral infection is not seen in India a. Dengue b. Japanese encephalitis c. Yellow fever d. West Nile encephalitis

1 Mark

40.

Alpha fetoprotein levels are elevated in a. Hepatoma b. Colon cancer c. Prostate cancer d. Tongue cancer

1 Mark

41.

Pathognomonic feature of Rabies of a. Negri bodies b. Guarnieri bodies c. Molluscum boides d. Torres body

1 Mark

42.

Cold sterilization is done by a. Gamma rays b. Infrared rays c. Steam sterilization d. Ultraviolet rays

1 Mark

43.

Taxoplasma gondii infection in AIDS patients usually presents as a. Lymphadenopathy b. Encephalitis c. Chorioretinitis d. Pneumonia

1 Mark

44.

Drug of choice for enteric fever is a. Ceftriaxone b. Ciprofloxacin c. Amoxicillin d. Cotrimoxazole

1 Mark

45.

A Gram negative bacillus with lactose fermenting colonies on MacConkey agar was isolated from a patient presented with urinary tract infection. It was oxidase negative, catalase positive, indole positive, methyl red reaction positive. The pathogen is most likely a. Klebsiella pneuminiae b. Pseudomonas aeruginosa c. Proteus vulgaris d. Escherichia coli

1 Mark

46.

A young rice field farmer develops high grade fever, jaundice and oliguria. Physical examination reveals conjunctival haemorrhage, petechiae and purpura. Reneal and liver function tests were found to be abnormal. The presentation is most likely caused by a. Treponema pallidum b. Leptospira interrogans c. Borrelia recurrentis d. Brucella melitensis

1 Mark

47.

Drug of choice of Syphilis is a. Penicillin b. Ciprofloxacin d. Ceftriaxone d. Azithromycin

1 Mark

48.

Best prognostic indicator in HIV infection is a. HIV RNA load b. CD4 T cell count c. CD8 T cell count d. p24 antigen

1 Mark

49.

Clue cells are useful in diagnosis of a. Vaginal candidiasis b. Trichomonal vaginitis c. Bacterial vaginosis d. Chancroid

1 Mark

50.

A 25 year old male presents with fever, splenomegaly, hepatomegaly, weight loss, Blood test reveals pancytopenia and examination of bone marrow aspirate by Giemsa stain reveals amastigote forms inside macrophages. The most likely diagnosis is a. Visceral leishmaniasis b. African sleeping sickness c. Chaga's disease d. Babesiosis

1 Mark

51.

Most common cause of non gonococcal urethritis is a. Chlamydia trachomatis b. Mycoplasma hominis c. Ureaplasma urealyticum d. Candida albicans

1 Mark

52.

Contaminated fried rice is associated with food poisoning with onset within 1-6 hours is caused by a. Staphylococcus aureus b. Bacillus cereus c. Clostridium perfringens d. Campylobacter jejuni

1 Mark

53.

A 25 year old sexually active male presents with genital ulcers which are painful, multiple, tiny and vesicular in nature. He gives a history of similar episode in the past 1 year. The most like disease is a. Donovanosis b. Lymphongranuloma venereum c. Genital herpes d. Chancroid

1 Mark

54.

Bacillary dysentery in India is commonly caused by a. Shigella flexneri b. Shigella boydii c. Shigella sonnei d. Shigella dysenteriae

1 Mark

55.

A 20 year old male presents with keratitis. We mount examination of Corneal scrapings reveals trophozoites with spine like pseudopodia, The most likely pathogen is a. Toxoplasma gondii b. Trypanosome cruzi c. Acanthamoeba species d. Onchocerca volvulus

1 Mark

56.

Highest mortality in pregnancy is associated with a. Hepatitis A b. Hepatitis B c. Hepatitis E d. Hepatitis C

1 Mark

57.

The classic triad of congenital rubella syndrome does not include a. Ear defect b. Ocular defects c. Cardiac defects d. CNS defects

1 Mark

58.

Scalded skin syndrom is mediated by a. Epidermolytic toxin b. Hemolysin c. Enterotoxin d. Deoxyribonuclease

1 Mark

59.

One of the following is not a oncogenic virus a. Epstein barr virus b. Cytomegalo virus c. Human herpes virus 8 d. Human papilloma virus

1 Mark

60.

A 10 year old boy presents with a tender, bright red, subcutaneous swelling on right cheek. The lesion is indurated with peau d'orange texture of the involved skin and is associated with fever and chills.The most likely clinical diagnosis is a. Erysipelas b. Impetigo c. Carbuncle d. Furuncle

1 Mark

61.

The drug of choice for rat bite fever is a. Penicillin b. Ciprofloxacin c. Ceftriaxone d. Azithromycin

1 Mark

62.

A HIV positive patient develops persistent, profuse diarrhea. Stool examination by acid fast stain by kinyoun's method reveals round, uniformly stained oocyst which is 4-6 microns size. The most likely etiological agent is a. Cyclospora b. Cryptosporidium c. Cystoisospora d. Giardia

1 Mark

63.

Plague is transmitted by a. Sand fly b. Rat flea c. Hard tick d. Soft tick

1 Mark

64.

A 30 year old male presents with acute pain in the right hypochondrium associated with high grade fever. Ultrasound guided liver aspiration revealed thick chocolate brown colored pus. Last portion of the aspirated pus demonstrated actively motile trophozoites with pseudopodia. The most likely etiological agent is a. Entamoeba histolytica b. Echinococcus granulosus c. Fasciola hepatica d. Clonorchis sinensis

1 Mark

Dr. NTR University of Health Sciences Bachelor of Medicine and Bachelor of SurgeryMicrobiology Previous Year Question Papers