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KNRUHS MBBS Pathology January 2026 (MB2019113 Regular)

MB2019113Kaloji Narayana Rao University of Health Sciences · Pathology · 2026 · January · Regular

Questions (25)

  1. 1.Lymphocytosis is not associated with: a) Infectious mononucleosis b) Mumps c) German measles d) Parasitic infestations
    1 Mark
  2. 2.Microcytic blood picture is seen in all except a) Thalassemia b) Sideroblastic anaemia c) Pernicious anaemia d) Anaemia of chronic disorders
    1 Mark
  3. 3.Total iron binding capacity is raised in a) Iron deficiency anaemia b) Renal disease c) Malignant disease d) Infections
    1 Mark
  4. 4.Defective platelet aggregation is seen in a) Bernard-Soulier syndrome b) Glanzman’s syndrome c) Haemophilia d) Vitamin K deficiency
    1 Mark
  5. 5.An young man met with a road accident and had left femoral fracture after which his leg was immobilized in a plaster cast for 6 weeks following which the diameter of the left calf was decreased in size. This change in size is most likely to result from which of the following alterations in his calf muscles? a) Hyperplasia b) Atrophy c) Dystrophy d) Hyalinosis
    1 Mark
  6. 6.In case of tissue subjected to hypoxic damage the cells in this tissue begin to swell with chromatin clumping in cell nuclei, ATPases are activated, and ATP production decreases. Which of the following ions accumulating in mitochondria and the cytosol contributes most to these findings and to eventual cell death? a) Ca2+ b) Cl- c) HCO3- d) K+
    1 Mark
  7. 7.A child with a history of recurrent infections with pyogenic bacteria had an area of soft tissue necrosis and the microscopic examination of the biopsy obtained from this tissue showed microbial organisms, but very few neutrophils. The analysis of the case showed neutrophil functional defect involving rolling. The most probable cause of increased susceptibility to infection is a defect involving which of the following molecules? a) Selectins b) Complement C3b c) Integrins d) Leukotriene B4
    1 Mark
  8. 8.Diabetic foot is an example of: a) Dry gangrene b) Wet gangrene c) Gas gangrene d) Necrotizing inflammation
    1 Mark
  9. 9.Enzyme which prevents cell ageing a) Catalase b) Superoxide dismutase c) Metalloproteinase d) Telomerase
    1 Mark
  10. 10.Amyloidosis results from abnormal folding of proteins, which are insoluble, aggregate, and deposit as: a) Fibrils in extracellular tissues b) Intracellular deposits c) Intranuclear inclusions d) In the meninges
    1 Mark
  11. 11.Define Necrosis. Discuss in detail about different types of Necrosis with suitable examples.
    15 Marks
  12. 12.A 2-year-old child was brought Paediatric outpatient with history of failure to thrive. O/E child is Anaemic with mongoloid face, i.e. with Malar Eminence, Frontal bossing, X-ray skull shows hair on end appearance, moderate splenomegaly and hepatomegaly. What is your provisional diagnosis? Discuss about pathogenesis and lab diagnosis of this condition.
    15 Marks
  13. 13.Fat Embolism.
    6 Marks
  14. 14.Special stains used to demonstrate Amyloid.
    6 Marks
  15. 15.Classify Hodgkin’s disease. Add a note on Nodular Sclerosis.
    6 Marks
  16. 16.WHO classification of AML.
    6 Marks
  17. 17.Down’s syndrome.
    6 Marks
  18. 18.Ochronosis.
    6 Marks
  19. 19.Complications of Wound Healing.
    6 Marks
  20. 20.Differences between Transudate and Exudate.
    3 Marks
  21. 21.Bence Jones Protein.
    3 Marks
  22. 22.CSF in Pyogenic Meningitis.
    3 Marks
  23. 23.Microscopy of Rhinosporidiosis.
    3 Marks
  24. 24.Granuloma.
    3 Marks
  25. 25.Bone marrow picture in B12 deficiency.
    3 Marks

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