KNRUHS MBBS Pharmacology January 2025 (MB2019111 Regular)

MB2019111Kaloji Narayana Rao University of Health Sciences · Pharmacology · 2025 · January · Regular

Questions (25)

1.Redistribution is a feature of a) highly lipid soluble drugs b) poorly lipid soluble drugs c) depot preparations d) highly plasma protein bound drugs
1 Mark
2.If the effect of combination of two drugs is equal to or greater than the sum of their individual effects, the two drugs are exhibiting: a) Tachyphylaxis b) Synergism c) Cross tolerance d) Antagonism
1 Mark
3.Prolonged lithium therapy can cause: a) Diabetes mellitus b) Goitre c) Parkinsonism d) Gout
1 Mark
4.The following are the Orphan drugs Except a) Fomepizole b) Acetyl Cysteine c) Erythropoietin d) Flumazenil
1 Mark
5.Which of the following anticholinergic agents is a CNS depressant a) Atropine b) Scopolamine c) Dicyclomine d) Oxyphenonium
1 Mark
6.Alpha 1 Blocker without any effect on blood pressure a) Prazosin b) Doxazosin c) Tamsulosin d) Terazosin
1 Mark
7.All of the following are reversible inhibitors of cyclo-oxygenase except a) Diclofenac b) Aspirin c) Ibuprofen d) Indomethacin
1 Mark
8.Choose the correct statement below a) Acidic drugs are largely ionized at acid gastric PH b) Basic drugs attain higher concentration extracellularly c) Weakly acidic drugs, ionize more at alkaline PH d) Weakly basic drugs ionize more at alkaline PH
1 Mark
9.Which of the following drug produce extra pyramidal side effect a) Metoclopramide b) Cisapride c) Domperidone d) All of the above
1 Mark
10.Directly acting skeletal muscle relaxants is a) Dantrolene sodium b) Pancuronium c) Succinyl choline d) Vecuronium
1 Mark
11.Classify Sedative Hypnotics. Write in brief the mechanism of action uses, adverse effects of Benzodiazepines
15 Marks
12.Classify Beta Blockers. Write in brief their uses and adverse effects add a note on Cardio Selective Beta Blockers?
15 Marks
13.Explain Drug Synergism with examples.
6 Marks
14.What is the first Pass Metabolism? Explain its significance.
6 Marks
15.Explain Pharmacogenetics with examples.
6 Marks
16.Describe the mechanism of action, uses and adverse effects of Carbamazepine.
6 Marks
17.List commonly used NSAIDs. Explain their mechanism of action and common adverse effects.
6 Marks
18.Describe the pharmacotherapy of status Asthmatics.
6 Marks
19.Describe how to motivate patients with long standing hypertension to adhere to the prescribed treatment of the physician.
6 Marks
20.Explain the rationale of using Tamsulosin in Benign Hypertrophy of Prostate (BHP).
3 Marks
21.List advantages of second generation Antihistaminics over conventional Antihistaminics.
3 Marks
22.Name two Mucolytics with indications for their use.
3 Marks
23.Name two Antimotility Drugs with indications and contraindications.
3 Marks
24.Explain why Geriatric age group requires special considerations while prescribing medications.
3 Marks
25.What is Eutectic Mixture of Local Anaesthetics (EMLA)? What is its indication?
3 Marks

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