KUHS MBBS Pharmacology Previous Question Paper - July 2023 (211001 2019 Scheme)

211001Kerala University of Health Sciences · Pharmacology · 2023 · July · 2019 Scheme

Questions (22)

1.A 52-year-old man presented with complaints of tightness and discomfort in middle part of chest, particularly after brisk walking. This is relived within 10 minutes of rest. A diagnosis of Angina pectoris was made by physician after appropriate investigations. (a) Mention four different drug groups used in treatment of Angina with two examples each. (b) Write the mechanism of action and adverse effects of Nitrates. (c) Outline the management of Acute pulmonary edema, with rationale for use of each drug. (d) Briefly describe Antiplatelet drugs.
15 Marks
2.A 29-year employee gradually stopped going out, withdrew socially. He felt guilty, worthless and tired all time, lost interest in pleasure and sex and had disturbed sleep. Physician diagnosed him a case of Major depression. (a) Enumerate three drug groups with two examples each to treat major depression. (b) Write the mechanism of action, uses and adverse effects of Fluoxetine. (c) Briefly describe Atypical Antipsychotics
15 Marks
3.Briefly describe drug biotransformation. Describe microsomal enzyme induction.
8 Marks
4.Aspirin
8 Marks
5.Classify Diuretics. Briefly describe Frusemide.
8 Marks
6.(a) Outline the management of Organophospherous poisoning. (b) Write the mechanism of action, therapeutic uses and adverse effects of Pancuronium.
8 Marks
7.Briefly describe Adrenaline. Advantage of combining Adrenaline with Lignocaine. Mention the sites where this combination is contraindicated.
8 Marks
8.Pharmacological management of Bronchial Asthma.
4 Marks
9.Streptokinase
4 Marks
10.Pharmacotherapy of Alcohol dependence.
4 Marks
11.What is the rationale of using Beta-blockers in Glaucoma.
4 Marks
12.Therapeutic uses of Anti-histamines.
4 Marks
13.Choose the Appropriate Drug and Justify Codein / Bromhexine in dry cough.
1 Mark
14.Choose the Appropriate Drug and Justify Alpha Methyl Dopa / Losartan in pregnancy induced hypertension.
1 Mark
15.Drugs used in Absence seizures with two examples
1 Mark
16.Prodrugs with two examples
1 Mark
17.Drugs used to treat Bipolar illness with two examples
1 Mark
18.Drugs administered transdermally with two examples
1 Mark
19.Drugs used to treat Morphine poisoning with two examples
1 Mark
20.Uricosuric agents with two examples
1 Mark
21.Prostaglandin analogues with two examples
1 Mark
22.Aldosterone antagonist with two examples
1 Mark

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