KUHS MBBS Pharmacology Previous Question Paper - March 2024 (211001 2019 Scheme)

211001Kerala University of Health Sciences · Pharmacology · 2024 · March · 2019 Scheme

Questions (22)

1.A 65-year-old lady presented with pain in both knees more on the left side. The pain is worsened by walking or standing for some time. X-Ray of knee shows narrowing of joint space, mild effusion and osteophytic projections. A diagnosis of Osteoarthritis of knee is made. She gave past history of ischemic heart disease a year back which was treated by angioplasty and a stent was placed. (a) Classify Non-steroidal Anti-Inflammatory Drugs (NSAIDs). (b) Which NSAID will be suitable for reliving knee pain. Justify. (c) Which NSAID is to be avoided. Why. (d) Describe the mechanism of action, uses and adverse effects of Aspirin.
15 Marks
2.(a) Enumerate four drug groups used to treat Hypertension with two examples each. (b) Write the mechanism of action uses and adverse effects of any one group. (c) Describe the drugs used in management of Acute Myocardial infarction with rationale for use of each drug
15 Marks
3.Drugs used to treat Parkinsonism. Describe the Mechanism of action and adverse effects of levodopa.
8 Marks
4.Compare the Mechanism of action, uses and adverse effects of Thiazides and Loop diuretics.
8 Marks
5.Enumerate opioid receptors. Write the uses, adverse effects and contra indications for Morphine. Briefly describe the management of Morphine poisoning.
8 Marks
6.Compare Inhalational and intravenous general anesthetics
8 Marks
7.(a) Neostigmine. (b) Ondansetron.
8 Marks
8.Briefly describe enzyme induction and enzyme inhibition with suitable examples.
4 Marks
9.Sumatriptan.
4 Marks
10.Fixed drug combination of drugs
4 Marks
11.Mechanism of action and therapeutic indications of Atorvastatin
4 Marks
12.Pharmacotherapy of Anaphylactic shock with rationale for use of each drug.
4 Marks
13.Choose the Appropriate Drug and Justify Prazosin/Phentolamine for the treatment of Benign hypertrophy of prostate (BPH) in elderly patients
1 Mark
14.Choose the Appropriate Drug and Justify Colchicine/Allopurinol for the treatment of Acute gout
1 Mark
15.Carbonic anhydrase inhibitors used to treat glaucoma with two examples
1 Mark
16.Drugs for Hypertensive emergencies with two examples
1 Mark
17.Drugs having high first pass metabolism with two examples
1 Mark
18.Drugs used in bipolar disorder with two examples
1 Mark
19.Drugs used to treat Venous thromboembolism with two examples
1 Mark
20.Centrally acting skeletal muscle relaxants with two examples
1 Mark
21.Inhaled steroids in Bronchial Asthma with two examples
1 Mark
22.Drugs used for Smoking cessation with two examples
1 Mark

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