KNRUHS MBBS Pharmacology August 2025 (MB2019111 Regular)

MB2019111Kaloji Narayana Rao University of Health Sciences · Pharmacology · 2025 · August · Regular

Questions (25)

1.Drug administered through the following route is most likely to be subjected to first-pass metabolism: a) Oral b) Sublingual c) Subcutaneous d) Rectal
1 Mark
2.Orphan drugs are a) drugs with high therapeutic failure b) drugs for rare disease c) drugs having low therapeutic margin d) drugs with high toxicity
1 Mark
3.Low doses of aspirin prolong bleeding time by selectively inhibiting synthesis of the following mediator in the platelets: a) Thromboxane A2 b) 5-Hydroxytryptamine c) Platelet activating factor d) Prostacyclin
1 Mark
4.The most effective drug in parkinsonism is: a) Bromocriptine b) Selegiline c) Levodopa d) Biperiden
1 Mark
5.The following analgesic lacks anti-inflammatory action: a) Paracetamol b) Ibuprofen c) Diclofenac sodium d) Piroxicam
1 Mark
6.The drug which undergoes 'Hofmann' elimination is: a) Succinylcholine b) Pancuronium c) Vecuronium d) Atracurium
1 Mark
7.fomepizole is used in which poisoning a) methyl alcohol poisoning b) morphine poisoning c) strychnine poisoning d) atropine poisoning
1 Mark
8.Atropine poisoning causes all except a) Dilated pupil b) Excessive salivation c) Excitement d) hot skin
1 Mark
9.Antidote for paracetamol poisoning is a) Naloxone b) Methylene blue c) N-acetylcysteine d) Flumazenil
1 Mark
10.The drug of choice for status epilepticus is a) Lorazepam b) Propofol c) Thiopentone d) Sodium valproate
1 Mark
11.a) Enlist the different types of receptors with examples of drugs acting through them. b) Describe the factors modifying drug action and their clinical significance.
15 Marks
12.Classify Antidepressants. Describe the mechanism of action, therapeutic uses and adverse effects of Tricyclic Antidepressants.
15 Marks
13.Describe the advantages and disadvantages of Intravenous route of Drug administration.
6 Marks
14.Compare and contrast Succinylcholine and D-Tubocurarine.
6 Marks
15.Describe therapeutics uses and adverse effects of Alpha Blockers.
6 Marks
16.Classify Anticholinesterases and mention their therapeutic uses.
6 Marks
17.Explain the mechanisms of action, therapeutic uses and adverse effects of proton Pump Inhibitors.
6 Marks
18.Describe disease modifying Anti Rheumatoid Drugs.
6 Marks
19.Describe how to counsel HIV/ AIDS patient to adhere to Anti-Retroviral Therapy.
6 Marks
20.Define Prodrug with two examples.
3 Marks
21.Enlist any two uses of Adrenaline with its rationale.
3 Marks
22.Mention the drugs used in the management of Organo Phosphorous Poisoning with its rationale.
3 Marks
23.Mention three different groups of drugs used in Bronchial Asthma with one example for each.
3 Marks
24.What is Malignant Hyperthermia? Mention the drug used for its treatment.
3 Marks
25.Define Tachyphylaxis. Give two examples of drugs causing Tachyphylaxis.
3 Marks

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