KNRUHS MBBS Pharmacology June 2025 (MB2019111 Regular)

MB2019111Kaloji Narayana Rao University of Health Sciences · Pharmacology · 2025 · June · Regular

Questions (25)

1.A prodrug is: a) the prototype member of a class of drugs b) the oldest member of a class of drugs c) an inactive drug that is transformed in the body to an active metabolite d) that drug stored in body tissues and released gradually in the circulation
1 Mark
2.The antiasthma drug which cannot be administered by inhalation route is: a) Theophylline b) Ipratropium bromide c) Budesonide d) Terbutaline
1 Mark
3.Dissociative anaesthesia' is produced by: a) Ketamine b) Fentanyl c) Propofol d) Both A & B
1 Mark
4.Which is the most important drug in the treatment of organophosphorus poisoning: a) Atropine sulfate b) Atenolol c) Diazepam d) Adrenaline
1 Mark
5.Carbamazepine is not used in a) Mania b) Partial seizure c) Trigeminal neuralgia d) Migraine
1 Mark
6.Among the disease modifying anti-rheumatic drugs, fastest symptom relief is obtained with: a) Auranofin b) Hydroxychloroquine c) Sulfasalazine d) Methotrexate
1 Mark
7.Drugs having both alpha and beta agonist property a) Propranolol b) Adrenaline c) dopamine d) Diazepam
1 Mark
8.Which of the following adrenergic agents increases peripheral vascular resistance a) Noradrenaline b) Adrenaline c) Isoprenaline d) None of the above
1 Mark
9.Orphan drugs are a) drugs for rare disease b) drugs with high therapeutic failure c) drugs having low therapeutic margin d) drugs with high toxicity
1 Mark
10.Which of the following is used as nasal decongestant a) Clonidine b) Dobutamine c) Norepinephrine d) Oxymetazoline
1 Mark
11.a) Define Biotransformation. Describe the consequences of Biotransformation reactions with examples. b) Define Enzyme induction and describe its clinical significance.
15 Marks
12.Classify Antiparkinsonian Drugs. Describe the mechanism of action and adverse effects of Levodopa. Enlist the benefits of combining Levodopa with Carbidopa.
15 Marks
13.Define apparent Volume of distribution. Describe its clinical significance.
6 Marks
14.Compare and contrast Benzodiazepines and Barbiturates.
6 Marks
15.Enlist atropine substitutes and their Therapeutic uses.
6 Marks
16.Describe the drugs used in the treatment of Cough.
6 Marks
17.Explain the mechanism of action, therapeutic uses and adverse effects of Ondansetron.
6 Marks
18.Enlist Prostaglandin Analogues. Describe their Therapeutics uses.
6 Marks
19.Describe how to motivate patients with coronary artery disease to adhere to the prescribed treatment of the physician.
6 Marks
20.Define Teratogenicity with two examples.
3 Marks
21.Mention the drugs used in the management of Myasthenia Gravis with its rationale.
3 Marks
22.Enlist any two Inhalational Corticosteroids used in Bronchial Asthma with their advantages.
3 Marks
23.Mention three drugs used in generalised Tonic Clonic Seizures.
3 Marks
24.Define Pharmacogenetics. Give two examples.
3 Marks
25.Mention three advantages of using aluminium Hydroxide and Magnesium Hydroxide as antacid combination.
3 Marks

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