KUHS MBBS Microbiology Previous Question Paper - February 2022 (216001 2019 Scheme)

216001Kerala University of Health Sciences · Microbiology · 2022 · February · 2019 Scheme

Questions (22)

1.A 5-year-old girl was brought in by her mother with the symptoms of fever, vomiting (7-8 episodes) and altered sensorium for the last 24 h. Central nervous system examination showed that she was drowsy, had signs of meningeal irritation, neck rigidity. Examination of CSF showed neutrophilic predominance. (a) What is the clinical diagnosis. (b) Name SIX common probable causes of this clinical condition. (c) Name two rapid tests to detect these causes. (d) What are the confirmatory tests that can be done in the laboratory. (e) Name the antimicrobial given empirically for this condition.seen. (f) Give details of vaccines available for these microbial agents. Name two other drugs which can be used for treating this condition (g)Give details of vaccines available for these microbial agents
15 Marks
2.A 21-year-old female presented with recurrent episodes of seizures, headache and vomiting and vertigo. MRI of the brain showed multiple ring enhancing lesions in the brain parenchyma. The causative agent was thought to be a cestode. (a) What is the probable causative agent. (b) Which is the infective stage of the parasite responsible for the above-mentioned condition. (c) What is the mode of transmission. (d) Name other four cestodes with their definitive hosts. (e) Name two stool concentration methods. (f) How do you treat the patient. (g) How to prevent this infection.
15 Marks
3.MRSA – mechanism of resistance, detection and treatment of cases and carriers, prevention.
8 Marks
4.Discuss laboratory diagnosis of LRTI.
8 Marks
5.What is antigenic shift and drift in influenza virus. What are the implications. What are the risk factors for complications following influenza infection
8 Marks
6.Explain the reasons that helped successful eradication of smallpox.
8 Marks
7.Cryptococcal meningitis – risk factors, pathogenesis and laboratory diagnosis
8 Marks
8.List risk factors that can lead to disseminated herpes infection and the common manifestations seen.
4 Marks
9.Tzanck smear.
4 Marks
10.Vaccine against Varicella zoster virus.
4 Marks
11.MMR vaccine
4 Marks
12.A swab is collected from an abscess in the ward. The details of the patient on the sample container do not match those on the request form. Discuss the correct decision and the appropriate action to be taken.
4 Marks
13.List TWO common viral causes of community acquired pneumonia.
1 Mark
14.What is the mechanism of action of the virulence factor in diphtheria.
1 Mark
15.Schedule and dosage of DPT vaccine.
1 Mark
16.List two common bacterial causes of healthcare acquired pneumonia.
1 Mark
17.What is the pathognomonic clinical feature of measles.
1 Mark
18.List modes of transmission of molluscum contagiosum.
1 Mark
19.Name two viruses which can cause latent infections.
1 Mark
20.Define mycetoma and give examples of two causative agents.
1 Mark
21.Name the reservoir of infection and method of transmission of Penicillium marneffei infection.
1 Mark
22.Sample, from the respiratory tract, received for Ziehl Neelsen stain is found to be mainly saliva. Discuss the correct decision and the appropriate action to be taken.
1 Mark

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