KUHS MBBS Pathology Previous Question Paper - July 2022 (213001 2019 Scheme)

213001Kerala University of Health Sciences · Pathology · 2022 · July · 2019 Scheme

Questions (22)

1.A seven-year-old boy presented to the hospital with breathlessness and severe pallor. On examination he had stunted growth, frontal bossing, mild icterus and moderate splenomegaly. History of repeated blood transfusions was present. Investigations revealed Hb- 3gm%, TLC – 5600/cu.mm, platelets – 3.0 lakhs/cu.mm. Peripheral smear showed microcytic hypochromic blood picture with marked anisopoikilocytosis, many target cells and reticulocyte count of 5%. (a) What is the likely diagnosis and why (b) What is the pathogenesis of this condition (c) What are the laboratory investigations needed in such a case to diagnose the disease and the expected results (d) How do you classify this disease based on its clinicohematological profile.
15 Marks
2.Define shock. Classify shock. Discuss the etiopathogenesis of septic shock. Discuss the different stages of shock.
15 Marks
3.Pictorially describe the extrinsic and intrinsic pathway of coagulation. Mention the tests used in their assessment with their normal ranges.
8 Marks
4.What are the types of Leukemoid reaction. Discuss the causes.
8 Marks
5.Discuss the different causes of cell injury with examples.
8 Marks
6.List the components of Virchow’s triad. Describe how each of the components leads to thrombosis with suitable examples
8 Marks
7.Define granulomatous inflammation. Describe the pathogenesis and morphological features of any one type of granuloma
8 Marks
8.Define amyloid. Name the stains used for demonstration of amyloid.
4 Marks
9.Immune thrombocytopenic purpura (ITP).
4 Marks
10.Type 1 Hypersensitivity reaction
4 Marks
11.Leucoerythroblastic blood picture – definition and causes
4 Marks
12.Discuss chemical carcinogenesis with examples
4 Marks
13.Type of necrosis seen in myocardial infarction is ______________.
1 Mark
14.Stain used to demonstrate myeloblasts in acute leukemia is __________________.
1 Mark
15.Autoantibody in Sjogren’s disease is _______________________
1 Mark
16.The fixative used for cervical cytology smear is ______________________
1 Mark
17.What is the cytogenetic abnormality seen in Burkitt Lymphoma.
1 Mark
18.What is LE cell
1 Mark
19.Name two oncogenic viruses and the malignancy they cause
1 Mark
20.What is Barr body.
1 Mark
21.Name two anticoagulant and their use
1 Mark
22.What is the difference between hypertrophy and hyperplasia
1 Mark

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