KUHS MBBS Pathology Previous Question Paper - December 2024 (213001 2019 Scheme)

213001Kerala University of Health Sciences · Pathology · 2024 · December · 2019 Scheme

Questions (30)

1.N-myc is a a) Signal transduction factor b) Growth factor c) Growth factor receptor d) Nuclear transcription factor
1 Mark
2.Translocation seen in Burkitt’s lymphoma is a) t(8:14) b) t(9:22) c) t(14:18) d) t(15:17)
1 Mark
3.The typical karyotype of Turner syndrome is a) 45, XO b) 46, XY c) 47, XXY d) 47, XYY
1 Mark
4. Lipofuscin deposition is most likely due to a) Autophagocytosis b) Necroptosis c) Pyroptosis d) Apoptosis
1 Mark
5.The action of putrefactive bacteria in necrosed tissue results in a) Coagulative Necrosis b) Infarction c) Wet Gangrene d) Caseation
1 Mark
6.Which of the following are antioxidants 1) Catalase 2) Myeloperoxidase 3) Glutathione peroxidase 4) Superoxide dismutase a) 1, 2, 3 b) 2, 3, 4 c) 3, 4, 1 d) 1, 2, 4
1 Mark
7.Examples for hypertrophy includes 1) Body builders 2) Myometrium of pregnant uterus 3) Fibroadenoma 4) Left ventricle in Hypertension a) 1, 2, 3 b) 2, 3, 4 c) 3, 4, 1 d) 1, 2, 4
1 Mark
8.T cell mediated disease includes 1) Rheumatoid arthritis 2) Psoriasis 3) Multiple sclerosis 4) Polyarteritis nodosa a) 1, 2, 3 b) 2, 3, 4 c) 3, 4, 1 d) 1, 2, 4
1 Mark
9.Classical Hodgkin lymphoma subtypes are 1) Nodular lymphocyte predominant 2) Mixed cellularity 3) Nodular sclerosis 4) Lymphocyte depleted a) 1, 2, 3 b) 2, 3, 4 c) 3, 4, 1 d) 1, 2, 4
1 Mark
10.Clinical features of cystic fibrosis includes 1) Sinusitis 2) Bronchial asthma 3) Cirrhosis 4) Meconium ileus a) 1, 2, 3 b) 2, 3, 4 c) 3, 4, 1 d) 1, 2, 4
1 Mark
11. (A): More than 70% of human cancers have a defect in p53 gene (R): p53 plays a central role in maintaining the integrity of the genome a) Both A & R are correct and R is the reason for A b) Both A & R are correct but R is not reason for A c) A is correct R is incorrect d) A is incorrect R is correct
1 Mark
12.(A): Type-1 hypersensitivity reaction causes laryngeal edema (R): Histamine causes increased vascular permeability and pain a) Both A & R are correct and R is the reason for A b) Both A & R are correct but R is not reason for A c) A is correct R is incorrect d) A is incorrect R is correct
1 Mark
13.(A): Dengue hemorrhagic fever causes thrombocytopenia (R): Increase in immune destruction of platelets a) Both A & R are correct and R is the reason for A b) Both A & R are correct but R is not reason for A c) A is correct R is incorrect d) A is incorrect R is correct
1 Mark
14.(A): IL-4 and IL-13 causes activation of M2 macrophages (R): M2 macrophages are not microbicidal a) Both A & R are correct and R is the reason for A b) Both A & R are correct but R is not reason for A c) A is correct R is incorrect d) A is incorrect R is correct
1 Mark
15.(A): Rotheras test detects proteins in urine (R): Nephrotic syndrome causes massive proteinuria a) Both A & R are correct and R is the reason for A b) Both A & R are correct but R is not reason for A c) A is correct R is incorrect d) A is incorrect R is correct
1 Mark
16.A 45 years old male presented to emergency department with difficulty in breathing, swelling of face, swollen lips, watering eyes and nose. He gave history of bee sting few minutes back.
Which of the following mediators suppress inflammation a) Prostaglandin b) Prostacyclin c) Leukotriene d) Lipoxin
Which of the following cytokine is NOT secreted by TH2 cells a) IL-4 b) IL-5 c) IFN-Gamma d) IL-13
The hypersensitivity reaction associated with this condition is a) Type-I b) Type-II c) Type-III d) Type-IV
Release of which of the following chemical mediators is most likely responsible for this finding a) Nitric oxide b) Prostaglandin E2 c) Complement C3b d) Histamine
Which of the following immunoglobulins play a major role in this reaction a) Ig A b) Ig G c) Ig E d) Ig M
5 Marks
17.A 35 year old male complains of fever, fatigue for the past 15 days. He had bleeding gums for the past 3 days. He had severe bone pains also. His total white blood cell count was 1,23,000 cells/c.mm with myeloblasts of 69%. a) What is your provisional diagnosis. b) Describe the peripheral smear and bone marrow findings. c) What other investigations are to be done for classifying the disease and assessing the prognosis of the patient.
10 Marks
18.Define Apoptosis. Give examples of physiologic and pathologic conditions associated with Apoptosis. Write in detail about mechanisms of Apoptosis.
10 Marks
19.Cytokines in inflammation.
6 Marks
20.Paraneoplastic syndromes.
6 Marks
21.CSF findings in different types of meningitis
6 Marks
22.Factors affecting wound healing.
6 Marks
23.Haemophilia A
6 Marks
24.Explain the pathogenesis of septic shock.
6 Marks
25. Define and classify Embolism.
4 Marks
26.Lab diagnosis of Megaloblastic anaemia.
4 Marks
27.Informed consent.
4 Marks
28.Rickets – Aetiopathogenesis and manifestations.
4 Marks
29.Transfusion reactions
4 Marks
30.Type II hypersensitivity reaction.
4 Marks

More from Pathology

Previous-year question paper.More papers →Report an issue