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KUHS MBBS Pathology Previous Question Paper - December 2024 (214001 2019 Scheme)

214001Kerala University of Health Sciences · Pathology · 2024 · December · 2019 Scheme

Questions (30)

  1. 1.Ghon focus is associated with a) Syphilis b) Tuberculosis c) Pneumonia d) Chronic bronchitis
    1 Mark
  2. 2.Risk factor associated with transitional cell carcinoma of urinary bladder is a) NSAID use b) Chronic smoking c) Chronic Alcoholism d) Urinary tract infections
    1 Mark
  3. 3.Hyperplastic arteriosclerosis and fibrinoid necrosis are associated with a) Membranoproliferative glomerulonephritis b) Analgesic abuse c) Malignant hypertension d) Diabetes mellitus
    1 Mark
  4. 4.Hemorrhagic pericardial effusion is seen in a) Infective endocarditis b) Metastatic carcinoma c) Acute myocarcial infection d) Rheumatic heart fever
    1 Mark
  5. 5.Krukenberg tumour of the ovary is an example of a) Hematogenous spread b) Lymphatic spread c) Transceloemic spread d) Perineural spread
    1 Mark
  6. 6.Which of the following are causes of hypercalcemia 1) Vitamin D intoxication 2) Acute pancreatitis 3) Sarcoidosis 4) Hyperparathyroidism a) 1, 2, 3 b) 2, 3, 4 c) 3, 4,1 d) 1, 2, 4
    1 Mark
  7. 7.Features of Cushings syndrome includes 1) Moon face 2) Impaired GTT 3) Thinning of the skin 4) Hypopigmentation a) 1, 2, 3 b) 2, 3, 4 c) 3, 4, 1 d) 1, 2, 4
    1 Mark
  8. 8.Squamous cell carcinoma of the esophagus is associated with 1) H. pylori infection 2) Chronic alcoholism 3) Tobacco usage 4) Plummer vinson syndrome a) 1, 2, 3 b) 2, 3, 4 c) 3, 4,1 d) 1, 2 ,4
    1 Mark
  9. 9.Risk factors of colorectal adenocarcinoma includes 1) Familial adenomatous polyp 2) Obesity 3) Low fiber diet 4) Intestinal amoebiasis a) 1, 2, 3 b) 2, 3, 4 c) 3, 4, 1 d) 1, 2, 4
    1 Mark
  10. 10.Syndromes associated with Wilms tumour are 1) WAGR 2) Gardner 3) Denys Drash 4) Beckwith Wiedemann a) 1, 2, 3 b) 2, 3, 4 c) 3, 4, 1 d) 1, 2, 4
    1 Mark
  11. 11.(A) Leukoplakia and Erythroplakia are mucosal plaques that may undergo malignant transformation. (R) The risk of malignant transformation is greater in leukoplakia than in erythroplakia. a) Both A & R are correct and R is the reason for A b) Both A & R are correct but R is not reason for A c) A is correct R is incorrect d) A is incorrect R is correct
    1 Mark
  12. 12. (A) Hepatocytes show PASD positive cytoplasmic globular inclusions in Alpha -1 -Antitrypsin deficiency. (R) Alpha-1-Antitrypsin deficiency is caused by mutations that lead to misfolding of Alpha -1-Antitrypsin a) Both A & R are correct and R is the reason for A b) Both A & R are correct but R is not reason for A c) A is correct R is incorrect d) A is incorrect R is correct
    1 Mark
  13. 13.(A) Migratory thrombophlebitis occurs in 10% of pancreatic carcinomas (R) Pancreatic carcinomas are associated with platelet aggregating factors, anticoagulants and necrotic products. a) Both A & R are correct and R is the reason for A b) Both A & R are correct but R is not reason for A c) A is correct R is incorrect d) A is incorrect R is correct
    1 Mark
  14. 14.(A) Intravesical administration of BCG (Bacillus Calmette Geurin) is a treatment for bladder carcinoma (R) BCG elicits granulomatous inflammation and local anti tumour immune response. a) Both A & R are correct and R is the reason for A b) Both A & R are correct but R is not reason for A c) A is correct R is incorrect d) A is incorrect R is correct
    1 Mark
  15. 15. (A) Osteoarthritis is a chronic inflammatory disease of autoimmune origin. (R) It is an intrinsic disorder of cartilage in response to mechanical and biochemical stress and failure of its repair a) Both A & R are correct and R is the reason for A b) Both A & R are correct but R is not reason for A c) A is correct R is incorrect d) A is incorrect R is correct
    1 Mark
  16. 16.A 53-year-old man has experienced severe chest pain for the past 6 hours. On physical examination he is afebrile, but has tachycardia. Laboratory studies show a serum troponin I of 10 ng/mL. A coronary angiogram is performed emergently and reveals >90% occlusion of the anterior interventricular (left anterior descending) artery.
    What is the key complication in the first 24 hours of an MI a) Fibrinous pericarditis b) Coronary artery aneurysm c) Arrhythmia d) Mitral insufficiency
    Which of the following cellular changes is associated with irreversible injury a) Glycogen stores are depleted b) Cytoplasmic sodium increases c) Nuclei undergo karyorrhexis d) Intracellular pH diminishes
    Which of the following vessel is commonly occluded in MI a) Left anterior descending b) Left circumflex c) Right anterior descending d) Right coronary artery
    What is the most sensitive and specific marker for a myocardial infarction (MI) a) AST b) LDH c) Troponin I d) CK-MB
    What are the classic signs of a cardiac tamponade a) Hypotension, muffled heart sounds, increased jugular venous distension (JVD) b) Tachycardia, dyspnoea, fever c) Bradycardia, weakness in arms, diaphoresis d) Hypertension, palpitations, chest pain
    5 Marks
  17. 17.A 65 year old male complains of dyspepsia, nausea, weightloss and loss of appetite since 6 months. Clinical examination reveals a mass palpable in the epigastric region. Endoscopy shows a proliferative growth near the stomach near the lesser curvature a) What is the probable diagnosis. b) Describe the aetiopathogenesis of the lesion. c) Classify and describe the morphology of the disease. d) Enumerate the usual sites of metastasis of this lesion.
    10 Marks
  18. 18.Describe in detail the etiopathogenesis, clinical features, morphology and complications of Atherosclerosis.
    10 Marks
  19. 19.Risk factors and prognostic factors of carcinoma breast.
    6 Marks
  20. 20.Types of Emphysema
    6 Marks
  21. 21.Germ cell tumors of testis.
    6 Marks
  22. 22.Classification of intestinal polyps
    6 Marks
  23. 23.Hashimotos thyroiditis – Aetiopathogenesis and morphology.
    6 Marks
  24. 24.Osteogenic sarcoma – Aetiopathogenesis and morphology.
    6 Marks
  25. 25.Retinoblastoma.
    4 Marks
  26. 26.Hydatidiform mole.
    4 Marks
  27. 27.Pathology of Hodgkin lymphoma
    4 Marks
  28. 28.Write briefly on the barriers to implementation of health as a universal right.
    4 Marks
  29. 29. Renal calculi – morphology and complications
    4 Marks
  30. 30.Basal cell carcinoma
    4 Marks

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