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NTRUHS MBBS Pharmacology February 2023 (15A03101 CBME) (QP 15A03101b)

15A03101Dr. NTR University of Health Sciences · Pharmacology · 2023 · February · CBME

Questions (20)

  1. 1.All of the following antimalarial drugs are 4-aminoquinoline derivatives EXCEPT a. Chloroquine b. Piperaquine c. Primaquine d. Amodiaquine
    1 Mark
  2. 2.Which of the following combination is the current gold standard treatment for HIV associated cryptococcal meningitis a. Flucytosine + Amphotericin B b. Fluconazole + Amphotericin B c. Voriconazole + Flucytosine d. Fluconazole + Caspofungin
    1 Mark
  3. 3.Which of the following antimicrotubular agent is used in the treatment of prostrate cancer a. Paclitaxel b. Docetaxel c. Estramustine d. Vincristine
    1 Mark
  4. 4.Which of the following amphotericin formulations is least like to cause infusion-related reactions a. Amphotericin B deoxycholate b. Amphotericin B colloidal dispersion c. Amphotericin B lipid complex d. Liposomal amphotericin B
    1 Mark
  5. 5.Cephalosporin used in MRSA infection a. Ceftaroline b. Ceftalozone c. Ceftazidime d. Cefotaxime
    1 Mark
  6. 6.The thiazolidinedione withdrawn from the market due to hepatoxicity is a. Pioglitazone b. Rosiglitazone c. Troglitazone d. Lobeglitazone
    1 Mark
  7. 7.Synthetic levothyroxine is stored in dark bottles to a. minimize spontaneous deiodination b. Avoid changes in brand bioavailability c. Improve efficacy d. Reduce product antigenicity
    1 Mark
  8. 8.Drugs inhibiting 5 - deiodinase and decreasing T3 level include ail of the following EXCEPT a. Lithium b. Amiodarone c. Beta-blockers d. Propylthiouracil
    1 Mark
  9. 9.The Selective Estrogen Receptor Modular (SERM) that is approved treatment of menopausal symptoms and for Prophylaxis of postmenopausal osteoporosis in combination with conjugated estrogen is a. Lasofoxifene b. Raloxifene c. Bazedoxifene d. Toremifene
    1 Mark
  10. 10.Antacid combinations for well sustained effect are most likely composed of a. Calcium and magnesium salts b. Calcium and aluminum salts c. Aluminum and magnesium salts d. Sodium bicarbonate and Magnesium salts
    1 Mark
  11. 11.QT interval prolongation occurs as an adverse effect of a. Domperidone b. Metoclopramide c. Cisapride d. Omeprazole
    1 Mark
  12. 12.Atropine is added to commercial preparations containing diphenoxylate to a. Potentiate anti-spasmodic effect b. To reduce excretion of salt and water c. To prevent overdosage and discourage opioid dependence d. To prolong its duration of action
    1 Mark
  13. 13.Which of the following metabolic adverse effect is caused by cyclosporine a. Hypokalemia b. Hyperkalemia c. Hypercalcemia d. Hypocalcemia
    1 Mark
  14. 14.Which of the following has immunostimulant action a. Prednisolone b. Levamisole c. Cyclosporine d. Thalidomide
    1 Mark
  15. 15.An Ectoparasiticide which induce CYP isoenzymes and produce cardiac arrhythmias is a. Permethrin b. Sulfur c. Crotamiton d. Lindane
    1 Mark
  16. 16.Which of the following type of Human papillomavirus (HPV) vaccine is used for prevention of cervical cancers in female a. Bivalent vaccine (HPV2) b. Quadrivalent vaccine (HPV4) c. Pentavalent vaccine (HPV5) d. 9 valent vaccine (HPV9)
    1 Mark
  17. 17.The following anti-epileptic can also be used in the management of obesity a. Valproate b. Lamotrigine c. Lacosamide d. Topiramate
    1 Mark
  18. 18.Which of the following is given to treat chemotherapy induced thrombocytopenia a. Epoetin alfa b. Plerixafor c. Filgrastim d. Oprelvekin
    1 Mark
  19. 19.Which of the following GP IIB/IIIa antagonist is a peptide a. Abciximab b. Tirofiban c. Eptifibatide d. Ticagrelor
    1 Mark
  20. 20.Anticoagulant that can be given in Heparin induced Thrombocytopenia (HIT) is a. Daiteparin b. warfarin c. Fondaparinux d. Enoxaparin
    1 Mark

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