RGUHS MBBS Microbiology March 2022 (1030 CBME)

1030Rajiv Gandhi University of Health Sciences · Microbiology · 2022 · March · CBME

Questions (30)

  1. 1.A 23 year old male patient from an endemic area came to the OPD with complaints of intermittent fever with chills and rigors, for the past 3 days. There was intense sweating following each fever episode. On examination he was febrile with temperature of 101°F and had mild Splenomegaly. Peripheral smear study shows the presence of parasites inside RBC’s a) Name the causative agent and the vector b) Describe the life cycle of the causative agent c) Write the pathogenicity of the causative agent d) Describe the laboratory diagnosis of the causative agent
    10 Marks
  2. 2.An adult patient was admitted in the hospital 5 days after a traumatic wound which was severely contaminated. The local muscles appeared to be crushed there was edema blackening and pain at the site. On examination, crepitus was felt at the site of injury a) What is the clinical diagnosis and the causative agent b) Name four spore bearing anaerobes c) Describe the pathogenesis of this condition d) Describe the laboratory diagnosis of this condition
    10 Marks
  3. 3.Draw a neat labelled diagram of a bacterial cell and write one function of each component
    5 Marks
  4. 4.Mention the various disinfectants used in hospitals and their uses
    5 Marks
  5. 5.Define immunity. Describe active immunity in detail
    5 Marks
  6. 6.Describe the principle, types and applications of ELISA
    5 Marks
  7. 7.Laboratory diagnosis of bacillary dysentery
    5 Marks
  8. 8.Laboratory diagnosis of Enteric fever
    5 Marks
  9. 9.Opportunistic infections in HIV patients
    5 Marks
  10. 10.Pathogenesis and laboratory diagnosis of Cholera
    5 Marks
  11. 11.Modes of transmission of hepatitis B infection
    3 Marks
  12. 12.Name three live vaccine and three killed vaccines
    3 Marks
  13. 13.Draw a labelled diagram of immunoglobulin M (IgM)
    3 Marks
  14. 14.Name three bacteria causing infective endocarditis
    3 Marks
  15. 15.Reynauld Braude phenomenon
    3 Marks
  16. 16.Name three viruses causing gastroenteritis
    3 Marks
  17. 17.Mention three extra intestinal manifestations of amoebiasis
    3 Marks
  18. 18.Antibiotic associated diarrhoea
    3 Marks
  19. 19.List the suppurative and non suppurative complications of Streptococcus pyogenes
    3 Marks
  20. 20.Name viruses causing skin rashes
    3 Marks
  21. 21.Who is considered as the father of antiseptic surgery? A. Louis pastuer B. Robert Koch C. Edward Jenner D. Joseph Lister
    1 Mark
  22. 22.The example of selective media A. Nutrient agar B. Blood agar C. Thiosulphate citrate bile salt sucrose agar D. Chocolate agar
    1 Mark
  23. 23.The following methods of diagnosis utilize labelled antibodies except A. Enzyme linked immunosorbent assay B. Radioimmunoassay C. Haemagglutination inhibition test D. Immunofluorescence
    1 Mark
  24. 24.All of these are major antigen presenting cells except A. T cells B. B cells C. Dendritic cells D. Macrophages
    1 Mark
  25. 25.A patient coming from Himachal Pradesh presents with multiple skin lesion. Microscopy reveals cigar shaped yeast cells and asteroid bodies. Microscopy of culture shows flower like pattern. Identify the agent A. Candida albicans B. Sporothrix schenkii C. Epidermophyton floccosum D. Rhizopus species
    1 Mark
  26. 26.Sclerotic bodies are seen in A. Mucormucosis B. Aspergillus C. Rhinosporidiosis D. Chromoblastomycosis
    1 Mark
  27. 27.Serological testing of a patient complaining of jaundice for 6 months revealed HbsAg (+ve) anti Hbs (-ve) anti HBcIgG (+ve) aHbeAg (+ve) and anti Hbe (-ve) The provisional diagnosis is A. Acute hepatitis with high infectivity B. Acute hepatitis with low infectivity C. Chronic hepatitis with high infectivity D. Chronic hepatitis with low infectivity
    1 Mark
  28. 28.Food poisoning within 4-6 hours of intake of food indicates presence of toxin of A. Staphyloccus aureus B. Clostridium perfringens C. Salmonella typhimurium D. V. cholerae
    1 Mark
  29. 29.Leishmania donovani can be cultivated in A. Blood agar B. NNN medium C. Diamonds medium D. RPMI medium
    1 Mark
  30. 30.The gene coding for core of HIV is A. Gag B. Env C. Pol D. Tat
    1 Mark

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