RGUHS MBBS Microbiology December 2024 (1030 CBME)

1030Rajiv Gandhi University of Health Sciences · Microbiology · 2024 · December · CBME

Questions (30)

1.A 9 year old boy from an overcrowded colony presented to the paediatric emergency department during monsoons with complaints of profuse and frequent watery diarrhoea since the previous day, accompanied by 2-3 episodes of vomiting. On examination, he was found to be moderately dehydrated. The stool on gross examination had a characteristic ‘Rice water’ appearance. a. What is the probable etiological diagnosis? b. Discuss in detail epidemiology and pathogenesis of the above condition c. Add a note on laboratory diagnosis
10 Marks
2.A 30 year old young adult with history of multiple sex partners is admitted with complaints of unexplained fever, weight loss, persistent diarrhoea and generalized lymphadenopathy for past 6 months. a) What is the probable diagnosis? b) Discuss the pathogenesis and laboratory diagnosis of the above condition c) What are the preventive measures for the above infection?
10 Marks
3.Describe tuberculin type of delayed hypersensitivity.
5 Marks
4.Describe classes of major histocompatibility complex and their role in Immunity.
5 Marks
5.A child presents with vesicular rashes. Rashes are bilateral, diffuse and centripetal in distribution. Fever appears with each crop of eruption. What is the probable clinical diagnosis & discuss the prevention of this infection
5 Marks
6.Differentiate eumycotic mycetoma from actinomycotic mycetoma
5 Marks
7.Sequence of events that occur following entry of quadri-nucleate cyst of Entamoeba histolytica into the gut
5 Marks
8.Describe the pathogenesis and the laboratory diagnosis of lepromatous leprosy.
5 Marks
9.Diarrheagenic Escherichia coli
5 Marks
10.Describe the differences between resistance acquired by mutation and transferrable drug resistance
5 Marks
11.Morphological classification of fungi with examples
3 Marks
12.Name three bacterial causes of food poisoning
3 Marks
13.Name three infections produced by Staphylococcus aureus.
3 Marks
14.What is occult filariasis?
3 Marks
15.Name three opportunistic sporozoa that cause diarrhea
3 Marks
16.Name three non-albicans species of Candida
3 Marks
17.List three Complications of falciparum malaria
3 Marks
18.Type and schedule of Hepatitis B vaccine
3 Marks
19.What are sequestered antigens? Give examples
3 Marks
20.List differences between active immunity and passive Immunity
3 Marks
21.Which of the cells are not associated with immune mechanisms? A. Basophils B. Dendritic cells C. Mast cells D. Epithelial cells
1 Mark
22.Tinea versicolor is caused by A. Candida albicans B. Trichophyton rubrum C. Trichophyton violaceum D. Malassezia furfur
1 Mark
23.False statement about dermatophytes A. Fungi that affect the keratinized layer of the skin B. Fungi affecting hair and nail C. They may be geophilic D. They do not grow at room temperature
1 Mark
24.Weil Felix reaction is based on A. Auto specificity B. Iso specificity C. Species specificity D. Heterogenic specificity
1 Mark
25.All of these are antigen presenting cells EXCEPT A. T cells B. B cells C. Dendritic cells D. Macrophage
1 Mark
26.During which of the following phases bacteria are most susceptible to antibiotics? A. Lag Phase B. Log phase C. Stationary phase D. Phase of decline
1 Mark
27.Who is the father of antiseptic surgery A. Robert Koch B. Paul Ehrlich C. Joseph Lister D. Alexander Fleming
1 Mark
28.During first week of enteric fever ,salmonellae can be isolated from all EXCEPT A. Bone marrow B. Blood C. Duodenal aspirate D. Urine sample
1 Mark
29.Babesiosis is transmitted by bite of A. Anopheles mosquito B. Sandfly C. Mite D. Tick
1 Mark
30.Causative agent of Calabar swelling is A. Dracunculus medinensis B. Wuchereria bancrofti C. Brugiya malayi D. Loa loa
1 Mark

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