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RGUHS MBBS Microbiology February 2024 (1030 CBME)

1030Rajiv Gandhi University of Health Sciences · Microbiology · 2024 · February · CBME

Questions (30)

  1. 1.A 55 year old male was admitted to the hospital with the complaints of severe pain in the lateral aspect of left lower limb. On examination the local area was found to be red, warm and tender. Pus was aspirated and sent for Gram’s stain and culture. Gram’s stain shows Gram positive cocci in chains. Culture has yielded beta – hemolytic colonies on blood agar. a. What is the clinical diagnosis and its causative organism? b. Mention four deep tissue infections caused by this organism. c. Mention four virulence factors of this organism. d. Briefly discuss laboratory diagnosis.
    10 Marks
  2. 2.A 31 year old man from Bihar presented with splenomegaly, anemia and fever. The Bone marrow aspirate collected was subjected to Giemsa staining which revealed Amastigotes filled within a macrophage. a. Identify the parasitic agent and clinical diagnosis. b. Write briefly about the life cycle of the etiological agent. c. What are the various diagnostic modalities? d. How will you treat this condition?
    10 Marks
  3. 3.Auto immunity.
    5 Marks
  4. 4.Laboratory diagnosis of Hepatitis B infection.
    5 Marks
  5. 5.Chemical disinfectants.
    5 Marks
  6. 6.Laboratory diagnosis of dengue haemorrhagic fever.
    5 Marks
  7. 7.Diagnosis, treatment and prophylaxis of Gas Gangrene
    5 Marks
  8. 8.Describe the morphology of bacteria with labelled diagram.
    5 Marks
  9. 9.An adult male complains of passing loose watery stools and vomiting since one day. On examination, patient is dehydrated. a. What is the presumptive clinical diagnosis? b. Enumerate viral and bacterial causes of diarrheoa c. Laboratory diagnosis of cholera
    5 Marks
  10. 10.Bacterial toxins
    5 Marks
  11. 11.Pathogenesis of shigellosis
    3 Marks
  12. 12.Prophylaxis of enteric fever.
    3 Marks
  13. 13.How will you demonstrate capsule?
    3 Marks
  14. 14.Mention three differences between Taenia saginata and Taenia solium.
    3 Marks
  15. 15.Laboratory diagnosis of Giardiasis.
    3 Marks
  16. 16.Mention three immunodeficiency diseases.
    3 Marks
  17. 17.Name three blood borne viral infections
    3 Marks
  18. 18.Mention three dermatophytes.
    3 Marks
  19. 19.Write the three common microbial agents causing Anaemia.
    3 Marks
  20. 20.Name three uses of ELISA
    3 Marks
  21. 21.The larval form of Hymenolepsis nana is A. Hydatid cyst B. Coenurus C. Cysticercus D. Cysticercoid
    1 Mark
  22. 22.Common name of Trichuris trichiura A. Pinworm B. Roundworm C. Whipworm D. Hookworm
    1 Mark
  23. 23.The correct sequence of manifestation seen in measles A. Fever, Koplik’s spots, rash B. Koplik’s spots, fever, rash C. Rash, fever, Koplik’s spots D. Rash, Koplik’s spots, fever
    1 Mark
  24. 24.Following Rubella vaccination, pregnancy should be avoided for atleast how many months? A. 1 month B. 2 months C. 3 months D. 6 months
    1 Mark
  25. 25.Gram stain morphology of Bacillus anthracis is A. Tennis racket appearance B. Drumstick appearance C. Bamboo stick appearance D. Spectacle glass appearance
    1 Mark
  26. 26.Bejel is caused by A. Treponema pertenue B. Treponema endemicum C. Treponema pallidum D. Treponema carateum
    1 Mark
  27. 27.MRSA is mediated due to A. Plasmid B. Mec A gene C. Transposons D. Chromosome
    1 Mark
  28. 28.Mechanism of direct transfer of free DNA A. Transformation B. Conjugation C. Transduction D. Transposition
    1 Mark
  29. 29.Which of the following viruses is enveloped? A. Poliomyelitis virus B. Adeno virus C. Herpes virus D. Parvovirus B19
    1 Mark
  30. 30.Spherules are seen in A. Rhinosporidiosis B. Chromoblastomycosis C. Mucor mycosis D. Aspergillosis
    1 Mark

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