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RGUHS MBBS Microbiology June 2024 (1030 CBME)

1030Rajiv Gandhi University of Health Sciences · Microbiology · 2024 · June · CBME

Questions (30)

  1. 1.Three members of a family who attended a gathering in a village complained of passing loose stools about 6 to 10 times per day. On examination all of them had signs of dehydration and stool samples collected appears like rice water a) Name the most probable causative bacterial agent b) Describe pathogenesis of this condition c) Describe laboratory diagnosis of this condition d) Outline the measures to manage this outbreak
    10 Marks
  2. 2.A commercial sex worker presents with intermittent fever, diarrhea and weight loss since two months. On examination she has oral thrush and enlarged lymph nodes in neck and axilla. Laboratory Investigation revealed that, serum was positive for P24 Antigen and her CD4 Count is less than 200 /mm a) Diagnose the most probable clinical condition and identify the causative agent of this clinical condition b) Describe pathogenesis of this clinical condition c) Describe laboratory diagnosis of the underlying primary disease d) Outline the medicolegal and ethical requirements that need to be met during laboratory diagnosis of this condition
    10 Marks
  3. 3.Bacterial conjugation and its implications
    5 Marks
  4. 4.ELISA – Principles, types and applications
    5 Marks
  5. 5.Delayed type hypersensitivity
    5 Marks
  6. 6.An Intravenous drug abuser develops fever with chills, myalgia, cardiac murmur. Methicillin Resistant Staphylococci aureus was isolated from Blood culture. Describe pathogenesis and laboratory diagnosis of this condition
    5 Marks
  7. 7.Laboratory diagnosis of lymphatic filariasis
    5 Marks
  8. 8.b. Pathogenesis and laboratory diagnosis of Hepatitis E infection.
    5 Marks
  9. 9.Superficial mycosis
    5 Marks
  10. 10.A middle-aged man presents with hypopigmented patches on his both forearms. On examination the lesions were non-scaly and had reduced sensations. Describe laboratory diagnosis of this condition
    5 Marks
  11. 11.Hot air oven – Principle and application
    3 Marks
  12. 12.Name three differences between exotoxin and endotoxin
    3 Marks
  13. 13.Major Histocompatibility Complex
    3 Marks
  14. 14.Differentiate primary and secondary immune response
    3 Marks
  15. 15.Name the major criteria of modified Jone’s criteria
    3 Marks
  16. 16.Draw a labelled diagram of the diagnostic form of visceral leishmaniasis found in bone marrow smears
    3 Marks
  17. 17.Name three bacterial causes of food poisoning
    3 Marks
  18. 18.Laboratory diagnosis of amoebic liver abscess
    3 Marks
  19. 19.Etiopathogenesis of Actinomycosis
    3 Marks
  20. 20.Name common infections caused by nonsporing anaerobes
    3 Marks
  21. 21.Spores are formed in _______ phase of bacterial growth curve A. Lag B. Log C. Stationary D. Decline
    1 Mark
  22. 22.Bacterium having polypeptide capsule is A. Neisseria meningitidis B. Bacillus anthracis C. Haemophilus influenzae D. Klebsiella pneumoniae
    1 Mark
  23. 23.Commonest cause of septic arthritis is A. Staphylococcus aureus B. Coagulase negative Staphylococcus Spp C. Streptococcus pneumoniae D. Escherichia coli
    1 Mark
  24. 24.Molecular mimicry as a mechanism of autoimmune response is seen in A. Rheumatic fever B. Rheumatoid arthritis C. Systemic lupus erythematosus D. Myasthenia gravis
    1 Mark
  25. 25.NOT a correct combination is A. Autograft – skin grafted to burn area B. Allograft – graft from genetically non-identical member of the same species C. Isograft – graft from heterozygous twin D. Xenograft – graft from different species
    1 Mark
  26. 26.A bridge between innate and acquired immunity is A. Complement components B. Neutrophils C. T lymphocytes D. Natural killer cells
    1 Mark
  27. 27.All of the following are dimorphic fungi EXCEPT A. Histoplasma capsulatum B. Blastomyces dermatitidis C. Cryptococcus neoformans D. Sporothrix schenckii
    1 Mark
  28. 28.Germ Tube test is positive in which of the following organisms A. C. albicans B. C. tropicalis C. C. parapsilosis D. C. auris
    1 Mark
  29. 29.A child aged 6 years vomited a white worm with cylindrical body measuring 20 cm. Parents gave history of passing similar worm in feces a few months ago. Stool examination showed many brown ova. Probable organism is A. Necator americanus B. Trichuris trichiura C. Taenia saginata D. Ascaris lumbricoides
    1 Mark
  30. 30.True about Strongyloides stercoralis is A. It can complete the life cycle independent of any host B. Infection is acquired by ingestion of embryonated ova C. Diagnosis is done by demonstrating ova in stool sample D. Commonly produces Loeffler syndrome
    1 Mark

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