RGUHS MBBS Microbiology February 2023 (1031 CBME)

1031Rajiv Gandhi University of Health Sciences · Microbiology · 2023 · February · CBME

Questions (30)

1.A two year old boy was brought to the hospital with history of high fever with vomiting and drowsiness. On examination the child has neck rigidity and other signs of meningitis. CSF examination was suggestive of bacterial meningitis a) List the bacteria causing acute meningitis b) Describe the pathogenesis of meningococcal meningitis c) Describe in detail sample collection and laboratory diagnosis of meningitis d) Discuss prevention of meningococcal meningitis
10 Marks
2.During the current pandemic, a 32 year old male who travelled from Britain developed fever, sore throat and loss of smell. On the 6th day he developed difficulty in breathing and drop-in oxygen saturation. CT thorax showed patches in lungs a) Mention the etiological diagnosis b) Discuss in detail the sample collection and laboratory diagnosis of this patient c) What precautions are to be followed by health care workers? d) How to segregate and handle the biomedical waste while caring for this patient?
10 Marks
3.1. Laboratory diagnosis of Bacterial vaginosis.
5 Marks
4.2. Laboratory diagnosis and treatment of Lympho-Granuloma Venereum (LGV).
5 Marks
5.3. Discuss Laboratory diagnosis of urinary tract infections.
5 Marks
6.Discuss pathogenesis, clinical features and laboratory diagnosis of Dengue fever.
5 Marks
7.Laboratory diagnosis of pulmonary TB.
5 Marks
8.Prophylaxis of Poliomyelitis.
5 Marks
9.Laboratory diagnosis and prevention of mucormycosis.
5 Marks
10.Define opportunistic infection and describe predisposing factors involved in opportunistic disease.
5 Marks
11.Post exposure prophylaxis of Rabies.
3 Marks
12.Lesions caused by HSV 2.
3 Marks
13.What is Prion disease? Mention three Prion diseases?
3 Marks
14.Mention three Arboviruses transmitted by mosquitoes
3 Marks
15.Enumerate three bacteria causing zoonosis
3 Marks
16.Laboratory diagnosis of diphtheria
3 Marks
17.Describe Weil-Felix test.
3 Marks
18.Discuss pathogenesis of pulmonary plague
3 Marks
19.Management of needle stick injury.
3 Marks
20.Mention the three components of standard precautions in health care delivery.
3 Marks
21.False statement regarding Japanese B encephalitis A. It is caused by flavivirus B. Transmitted by Aedes mosquito C. Endemic in India D. Man is dead end host
1 Mark
22.The type of diphtheria with highest mortality is A. Pharyngeal B. Nasal C. Cutaneous D. Conjunctival
1 Mark
23.Rabies is identified by A. Guarnieri bodies B. Negri bodies C. Cowdry bodies D. Paschen body
1 Mark
24.Which of the following is correct about Prions? A. Destroyed by autoclaving at 121 degree C B. Long incubation period C. Immunogenic D. Nucleic acid present
1 Mark
25.All of the following viruses cause viral meningitis EXCEPT A. Enteroviruses B. Herpes simplex virus C. Arbovirus D. Rotavirus
1 Mark
26.Carrom coin appearance of colonies is seen for A. S. pyogenes B. Viridans streptococci C. S. agalactiae D. S.pneumoniae
1 Mark
27.Neonatal meningitis acquired through infected birth canal is due to A. S. pyogenes B. Viridians streptococci C. S.agalactiae D. S.pneumoniae
1 Mark
28.All of following bacteria can cause acute bacterial meningitis EXCEPT A. Neisseria meningitidis B. Streptococcus pneumoniae C. Haemophilus influenzae D. Neisseria gonorrheae
1 Mark
29.Human acquired cysticercus cellulosae infection is NOT caused by A. Ingestion of contaminated vegetables B. Autoinfections C. Reverse peristalsis D. Ingestion of contaminated pig’s meat
1 Mark
30.Most common manifestation of Toxoplasma gondii in immunocompromised adult A. Lymphadenopathy B. Chorioretinitis C. Myocarditis D. Encephalitis
1 Mark

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