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RGUHS MBBS Microbiology June 2024 (1031 CBME)

1031Rajiv Gandhi University of Health Sciences · Microbiology · 2024 · June · CBME

Questions (30)

  1. 1.A lady aged 26 years presented with high grade fever with chills, headache since 4 days. On examination she had neck stiffness and Kernig’s sign was positive. CSF gram stain showed gram negative diplococci with adjacent flat surfaces. a) Identify the causative agent b) Describe the pathogenesis of this condition c) Describe laboratory diagnosis of this condition d) Suggest methods of prevention
    10 Marks
  2. 2.An adult man presented with fever, breathlessness, dry cough and loss of smell since 4 days. He had fever, sore throat and running nose in the previous week. RTPCR of nasopharyngeal swab showed presence of N and RdRp genes. a) Identify the causative agent b) Describe laboratory diagnosis of this condition c) Describe methods of prevention d) Suggest appropriate management of common biomedical waste generated while caring for this patient
    10 Marks
  3. 3.Pathogenesis and laboratory diagnosis of Japanese encephalitis
    5 Marks
  4. 4.Laboratory diagnostic strategy of pulmonary tuberculosis as per National Tuberculosis Elimination Program
    5 Marks
  5. 5.a. A lady aged 28 years presented with recurrent multiple painful vesicular lesions of external genitalia. Giemsa-stained smear of the base of the lesions showed multinucleated giant cells with faceted nuclei. Describe pathogenesis and laboratory diagnosis of this condition
    5 Marks
  6. 6.Pathogenesis and laboratory diagnosis of Leptospirosis
    5 Marks
  7. 7.Clinical features, complications and laboratory diagnosis of Dengue
    5 Marks
  8. 8.b. Pathogenesis and laboratory diagnosis of Hydatid cyst disease
    5 Marks
  9. 9.c. Risk factors and prevention of CAUTI
    5 Marks
  10. 10.d. Oncogenic viruses
    5 Marks
  11. 11.Describe the reasons for epidemics and pandemics of influenza
    3 Marks
  12. 12.Diagnosis of neurocysticercosis
    3 Marks
  13. 13.Morphology of Corynebacterium diphtheriae
    3 Marks
  14. 14.Name common infections caused by Aspergillus Spp
    3 Marks
  15. 15.Significant bacteriuria
    3 Marks
  16. 16.Laboratory diagnosis of lymphogranuloma venereum
    3 Marks
  17. 17.Draw a labelled diagram of Trichomonas vaginalis
    3 Marks
  18. 18.Name three organisms causing nongonococcal urethritis
    3 Marks
  19. 19.Malignant pustule
    3 Marks
  20. 20.Describe the ethical considerations while testing for HIV
    3 Marks
  21. 21.All the following are effective in preventing pharyngoconjunctival fever caused by Adenovirus EXCEPT A. Effective hand washing B. 70% ethanol to disinfect environmental surfaces C. Chlorination of swimming pools and waste water D. Strict asepsis during eye examinations
    1 Mark
  22. 22.True about tropical pulmonary eosinophilia is A. Microfilariae are not detected in peripheral smear B. Caused by migrating larvae of Ascaris lumbricoides C. Hyaline septate acutely-branching hyphae are seen in sputum D. Productive cough with blood-tinged purulent sputum is characteristic
    1 Mark
  23. 23.An immunocompromised individual has dry cough and breathlessness. Gomori’s methenamine silver stain of bronchoalveolar lavage showed black structures resembling crushed ping-pong balls. The probable causative agent is A. Pneumocystis jirovecii B. Talaromyces marneffei C. Histoplasma capsulatum D. Blastomyces dermatitidis
    1 Mark
  24. 24.An adult man has fever and purulent urethral discharge. Gram stain of the discharge showed gram negative diplococci with adjacent concave surfaces. Treatment of choice is A. Ceftriaxone B. Azithromycin C. Doxycycline D. Acyclovir
    1 Mark
  25. 25.True about standard tests for syphilis is A. Detect antibodies to treponemal antigens B. Can not differentiate recent and past infection C. Positive results irrespective of titers are significant D. Help in assessing response to treatment
    1 Mark
  26. 26.A lady has multiple painless dome-shaped, pink pearly wart-like umbilicated lesions, with a dimple at the center in perigenital area. Most useful test in this case is A. Demonstration of Molluscum bodies in biopsied lesion B. Leishman stained smear of the lesion to show Guarneri bodies C. Iodine-stained smear of lesion to demonstrate inclusion bodies D. Gram stain of lesion to show gram negative bacilli with safety-pin appearance
    1 Mark
  27. 27.Urine wet mount of a man with hematuria showed oval and elongated, non-operculated eggs measuring 150 × 50 μm, with a terminal spine. It is suggestive of A. Schistosoma haematobium B. Schistosoma mansoni C. Schistosoma japonicum D. Schistosoma urealyticum
    1 Mark
  28. 28.True about Kyasanur Forest Disease is A. Endemic in central African countries B. Transmitted by soft tick C. Monkeys are amplifier hosts D. Encephalitis is the characteristic feature
    1 Mark
  29. 29.True about human infection by Taenia solium is that A. Man can be definitive or intermediate host B. Non-bile-stained eggs C. Scolex is quadrangular without rostellum and hooklets D. Adult worm has cylindrical body
    1 Mark
  30. 30.True about infections caused by zoophilic dermatophytes is A. Commonest organism is Trichophyton rubrum B. Mild symptoms C. Resolve more quickly D. Can be grown only by using experimental animals
    1 Mark

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