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RGUHS MBBS Microbiology April 2025 (1031 CBME)

1031Rajiv Gandhi University of Health Sciences · Microbiology · 2025 · April · CBME

Questions (30)

  1. 1.A 20-year-old male was admitted to the hospital with fever, headache, nausea, confusion, restlessness, hallucination and difficulty in swallowing liquids. His friends mentioned that he had been bitten by a street dog two months ago. As the wound was neither deep nor painful, he was not taken to hospital then, instead simple wound cleaning was done at hostel without any medical treatment. After 2 days he developed painful spasm of the respiratory laryngeal and pharyngeal muscles and he died of respiratory failure. a) Draw a neat labelled diagram of causative agent b) Describe the pathogenesis of this condition c) Discuss the laboratory diagnosis. d) Add a note on post exposure prophylaxis for dog bite
    10 Marks
  2. 2.A 25-year-old male presented to STD clinic with a single, painless genital ulcer of 12days duration. He had a history of sexual exposure with a commercial sex worker. On examination the penile ulcer was hard and indurated along with inguinal lymph node enlargement. Blood sample was collected and sent for VDRL test. The test was reactive at 1:128 dilution. a) What is your diagnosis and mention the causative agent? b) Enumerate the other causative agents of genital ulcer c) Describe the laboratory diagnostic methods in above case d) Mention the complications of the above condition
    10 Marks
  3. 3.Aseptic meningitis
    5 Marks
  4. 4.Cryptococcal meningitis
    5 Marks
  5. 5.Laboratory diagnosis of pulmonary tuberculosis.
    5 Marks
  6. 6.Enumerate the viruses causing respiratory tract infections. Describe the laboratory diagnosis of viral Influenza
    5 Marks
  7. 7.Infectious mononucleosis.
    5 Marks
  8. 8.Neurocysticercosis.
    5 Marks
  9. 9.Discuss the preventive measures of surgical site infection.
    5 Marks
  10. 10.Enumerate the oncogenic viruses. Discuss the mechanism of viral oncogenesis
    5 Marks
  11. 11.Enumerate the causative agents of neonatal meningitis
    3 Marks
  12. 12.Prion diseases
    3 Marks
  13. 13.Draw a neat labelled diagram of hydatid cyst
    3 Marks
  14. 14.Hib Vaccine
    3 Marks
  15. 15.Loeffler’s syndrome
    3 Marks
  16. 16.Draw neat labeled diagram of Aspergillus niger
    3 Marks
  17. 17.Preventive measures of sexually transmitted diseases
    3 Marks
  18. 18.List three causative agents of discharge per vagina
    3 Marks
  19. 19.Clinical types of human Plague
    3 Marks
  20. 20.Enlist six opportunistic fungal agents.
    3 Marks
  21. 21.The most infective stage in whooping cough is A. Catarrhal stage B. Convalescent stage C. Paroxysmal stage D. All of the above
    1 Mark
  22. 22.Which of the following parasite does not pass through the lungs during its life cycle A. Strongyloides stercoralis B. A.duodenale C. A.lumbricoides D. T.trichiura
    1 Mark
  23. 23.Treatment of the sexual partner is generally not required in which of the following infections A. Bacterial Vaginosis B. Trichomoniasis C. Herpes viral infection D. Gonorrhea
    1 Mark
  24. 24.Inverted fir tree appearance on gelatin stab culture is a characteristic feature of A. Bacillus anthracis B. Coxiella burnetii C. Brucella melitensis D. Leptospira icterohaemorrhagica
    1 Mark
  25. 25.Which of the following is the most common etiological agent of UTI? A. Escherichia coli B. Staphylococcus aureus C. Pseudomonas aeruginosa D. Enterobacter spp
    1 Mark
  26. 26.Ophthalmia neonatorum is caused by which of the following? A. Listeria monocytogenes B. Moraxella catarrhalis C. Neisseria gonorrhoeae D. Hemophilus influenzae
    1 Mark
  27. 27.Which of the following is not an agent of non-Gonococcal urethritis? A. Chlamydia trachomatis B. Candida albicans C. Gardnerella vaginalis D. Mycoplasma hominis
    1 Mark
  28. 28.Which of the following virus possess haemagglutinin but not neuraminidase spikes A. Parainfluenza virus B. Pneumovirus C. Measles virus D. Respiratory syncytial virus
    1 Mark
  29. 29.All of the following infections are vector borne infections in India EXCEPT A. Dengue B. Chikungunya C. Japanese encephalitis D. Yellow fever
    1 Mark
  30. 30.Drug of choice for rat bite fever A. Amikacin B. Cephalosporin C. Penicillin G D. Tetracycline
    1 Mark

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