RGUHS MBBS Pathology February 2023 (1026 CBME)

1026Rajiv Gandhi University of Health Sciences · Pathology · 2023 · February · CBME

Questions (30)

1.A 12 year boy presented with sudden onset of fever and vomiting with abdominal pain. On palpation there is tenderness at MC Burney’s point a) What is the probable diagnosis? b) Define inflammation? Enumerate cellular events of inflammation c) Outcomes of acute inflammation
10 Marks
2.A 20 year male patient presented with swelling of both knees and pain for the past one week. He gives history of similar episodes earlier. He also gives history of excessive bleeding after minor injuries. His maternal uncle has similar complaints and has been treated by repeated blood transfusions following excessive bleeding episodes a) What are the probable differential diagnosis? b) What are the laboratory investigations required for the diagnosis? c) What is the etiopathogenesis of these disorders? d) How will you make the final specific diagnosis?
10 Marks
3.1. Opportunistic infections in AIDS
5 Marks
4.2. Define Amyloidosis? Write the physical and chemical nature of Amyloid and note on special stains
5 Marks
5.3. Describe the morphology of different types of infarcts with examples
5 Marks
6.Peripheral smear and bone marrow findings in megaloblastic anemia
5 Marks
7.Describe different types of cellular adaptations to stress with examples
5 Marks
8.Type III hypersensitivity reactions with examples
5 Marks
9.Define and classify anaemia according to aetiology
5 Marks
10.Describe the modes of spread of malignant neoplasms with examples
5 Marks
11.Differences in CSF findings between pyogenic and Tuberculous meningitis
3 Marks
12.Gaucher’s disease
3 Marks
13.Virchow’s triad
3 Marks
14.Advantages of fine needle aspiration cytology
3 Marks
15.Name three conditions with raised ESR
3 Marks
16.Primary wound healing
3 Marks
17.Bence-Jones protein
3 Marks
18.Peripheral smear findings in accelerated phase of chronic myeloid leukemia
3 Marks
19.Mandatory serological test in screening of blood donors
3 Marks
20.Immediate complications of blood transfusion
3 Marks
21.Which of the following pigment’s presence is a telltale sign of free radical injury A. Lipofuscin B. Melanin C. Bilirubin D. Hematin
1 Mark
22.Diapedesis is A. Movement of leucocytes in the extra vascular compartment B. Immigration of the leucocytes through the vessel wall at the site of inflammation C. Aggregation of lymphocytes at the site of bleeding D. Autodigestion of the cells
1 Mark
23.Which of the following organs are heart failure cells seen in A. Myocardium B. Lungs C. Liver D. Spleen
1 Mark
24.White infarct is seen in all EXCEPT A. Lungs B. Spleen C. Kidney D. Heart
1 Mark
25.Correct sequence of cell cycle is A. G0-M-G2-S-G1 B. G0-G1-G2-S-M C. G0-G1-S-G2-M D. G0-G1-S-M-G2
1 Mark
26.All of the following are examples of tumour markers EXCEPT A. Human chorionic Gonadotropin B. Alpha Fetoprotein C. Prostate specific antigen D. Cyclin D1
1 Mark
27.Antigen presenting cells present in skin are called A. Langerhans cells B. Kupffer cells C. Microglia D. Melanocytes
1 Mark
28.Which of the following is not true about innate immunity A. It is present prior to antigenic exposure B. It is relatively non-specific C. Memory is seen D. It is the first line of defence
1 Mark
29.Autoimmune haemolytic anemia is most likely to be associated with which of the following conditions A. Acute lymphoid leukemia B. Acute myeloid leukemia C. Chronic Myelogenous leukemia D. Chronic lymphocytic leukemia
1 Mark
30.Hypersegmented neutrophils are seen in A. Iron deficiency anaemia B. Megaloblastic anaemia C. Sickle cell anaemia D. Autoimmune hemolytic anaemia
1 Mark

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