RGUHS MBBS Pathology May 2023 (1026 CBME)

1026Rajiv Gandhi University of Health Sciences · Pathology · 2023 · May · CBME

Questions (30)

  1. 1.60 year old male presented with complaints of pedal edema and exertional dyspnoea. On investigation his Hemoglobin was 3.5 g/dl and he had raised brain natriuretic peptide. Blood pressure was 90/50 mm of Hg and heart rate was 60 bpm. He is not a diabetic or hypertensive. He was diagnosed with congestive heart failure. a) List the types of edema b) Identify the type of edema in the above clinical history c) Describe the pathophysiology, clinical features and consequences of this condition
    10 Marks
  2. 2.30 year old male on pure vegetarian diet presents with restlessness, fatigue, dizziness, tingling and numbness in his legs. On routine blood evaluation his hemoglobin was found to be 7gms/dl and MCV of 110 fl. Patient was also found to have reticulocytopenia a. What is the most probable diagnosis? b. Describe the etiology, pathogenesis, peripheral smear and bone marrow findings of Megaloblastic anemia.
    10 Marks
  3. 3.1. Differences between necrosis and apoptosis.
    5 Marks
  4. 4.2. Vascular changes in Acute inflammation.
    5 Marks
  5. 5.3. Chemical Carcinogenesis.
    5 Marks
  6. 6.Discuss different methods of blood grouping.
    5 Marks
  7. 7.Chronic Myeloid Leukaemia.
    5 Marks
  8. 8.Thalassemia major.
    5 Marks
  9. 9.Discuss various stains for amyloid.
    5 Marks
  10. 10.Classification of Hodgkin’s lymphoma.
    5 Marks
  11. 11.Metaplasia.
    3 Marks
  12. 12.Arthus reaction.
    3 Marks
  13. 13.Ghon’s complex.
    3 Marks
  14. 14.Tuberculoid leprosy.
    3 Marks
  15. 15.Exfoliative cytology.
    3 Marks
  16. 16.Define chemotaxis. Name two chemotactic agents
    3 Marks
  17. 17.Stages of E.S.R
    3 Marks
  18. 18.Auer rods.
    3 Marks
  19. 19.Fate of thrombus
    3 Marks
  20. 20.Causes of proteinuria.
    3 Marks
  21. 21.Vasoactive amines play an important role in vascular events of inflammation. Histamine causes all EXCEPT A. Smooth muscle contraction B. Decreased vascular permeability C. Increased permeability D. Increased secretions
    1 Mark
  22. 22.Which of the following is an example for labile cells A. Bone marrow B. Hepatocytes C. Neurons D. Fibroblasts
    1 Mark
  23. 23.Caspases are involved in A. Acute inflammation B. Chronic inflammation C. Apoptosis D. Regeneration
    1 Mark
  24. 24.24 year old male sustains multiple fratures of long bone in a road traffic accident. Which of the following stains is used to detect fat embolism A. Oil-red-O B. Best carmine C. PAS D. Von Kossa
    1 Mark
  25. 25.Starry sky appearances is seen in A. Large cell lymphoma B. Hodgkin’s lymphoma C. Burkitt lymphoma D. T – cell lymphoma
    1 Mark
  26. 26.ESR is increased markedly in A. Dengue fever B. Tuberculosis C. Malaria D. Typhoid
    1 Mark
  27. 27.Pernicious anemia is due to A. Iron deficiency B. Intrinsic factory deficiency C. Sickling of RBCs D. Red cell membrane deficiency
    1 Mark
  28. 28.Peripheral smear is reported as poikilocytosis in a patient with long standing anemia. Poikilocytosis refers to A. Different shapes of RBCs B. Different sizes of RBCs C. Inclusions in RBCs D. Increase in RBCs
    1 Mark
  29. 29.Hemophilia is a A. B12 deficiency anemia B. Type of leukemia C. Hemolytic anemia D. Bleeding disorder
    1 Mark
  30. 30.Gamna Gandy bodies are seen in A. Spleen B. Liver C. Oral cavity D. RBCs
    1 Mark

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