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RGUHS MBBS Pathology November 2025 (1026 CBME)

1026Rajiv Gandhi University of Health Sciences · Pathology · 2025 · November · CBME

Questions (30)

  1. 1.30-year female admitted to emergency with high grade fever, hypotension, weak, rapid pulse, tachypnea and cold, clammy, cyanotic skin. Blood culture showed gram negative bacteria. She succumbed due to dysfunction in multiple organs. a) What is the likely diagnosis? b) Discuss the etiopathogenesis of this condition. c) Describe the morphology of organs involved.
    10 Marks
  2. 2.30-year male vegetarian and chronic gastritis patient was evaluated for the pallor, paresthesia of extremities. a) What is the type of anemia? b) Discuss the etiopathogenesis and pathology associated with this condition c) Add a note on laboratory investigations in the work up of this patient.
    10 Marks
  3. 3.Laboratory diagnosis of systemic lupus erythematosus
    5 Marks
  4. 4.Differences between necrosis and apoptosis.
    5 Marks
  5. 5.Describe the sequential steps in cutaneous wound healing.
    5 Marks
  6. 6.List the actions of Arachidonic acid metabolites in inflammation.
    5 Marks
  7. 7.Role of Exfoliative cytology.
    5 Marks
  8. 8.Paraneoplastic syndromes.
    5 Marks
  9. 9.Opportunistic infection associated with AIDS.
    5 Marks
  10. 10.Discuss the pathophysiology of sickle cell anemia.
    5 Marks
  11. 11.Sputum findings in Bronchial asthma.
    3 Marks
  12. 12.Cytochemical stains used in Acute leukemia.
    3 Marks
  13. 13.Qualitative platelet defects.
    3 Marks
  14. 14.Aplastic anemia.
    3 Marks
  15. 15.Enumerate the blood products available for transfusion.
    3 Marks
  16. 16.List six examples for metaplasia
    3 Marks
  17. 17.Amyloid spleen.
    3 Marks
  18. 18.Rickets.
    3 Marks
  19. 19.List the causes associated with variation in urine specific gravity
    3 Marks
  20. 20.List the manifestations of syphilis.
    3 Marks
  21. 21.Which of the following is DNA repair defect? A. Retinoblastoma B. Neurofibromatosis C. Xeroderma pigmentosum D. MEN-I
    1 Mark
  22. 22.Type III Hypersensitivity reaction is seen in all EXCEPT A. Post streptococcal Glomerulonephritis B. Good Pasteur’s syndrome C. Systemic lupus erythematosus D. Rheumatoid arthritis
    1 Mark
  23. 23.Nut meg liver is seen in all conditions EXCEPT A. Hepatic venous congestion. B. Right heart failure C. Budd chiari syndrome D. Reye’s syndrome
    1 Mark
  24. 24.Dystrophic calcification is seen in all EXCEPT A. Old healed tuberculosis B. Damaged heart valves C. Fat necrosis D. Chronic kidney failure
    1 Mark
  25. 25.In Marfan’s syndrome there is defect in protein A. Dystrophin B. Spectrin C. Fibrillin D. Ankyrin
    1 Mark
  26. 26.Which of the following is a feature of Disseminated Intravascular Coagulation (DIC)? A. Normal prothrombin time B. Reduced plasma fibrinogen C. Normal platelet count D. Normal clotting time
    1 Mark
  27. 27.Carcinoembryonic antigen is elevated in all, EXCEPT A. Carcinoma pancreas B. Carcinoma colon C. Carcinoma stomach D. Carcinoma prostate
    1 Mark
  28. 28.7-year-old girl presents with haematoma in the thigh. She has prolonged APTT, normal PT and platelet count. This is due to deficiency of any of the factor EXCEPT A. Factor IX B. Factor VIII C. Factor VII D. Factor XI
    1 Mark
  29. 29.Which of the following is NOT a poor prognostic factor in Acute Lymphoblastic Leukemia? A. Presence of t (9:22) B. Age < 2 years C. Hyperploidy D. Peripheral blood blast count >1 lakh
    1 Mark
  30. 30.Autoimmune hemolytic anemia is seen in: A. Acute Lymphoblastic Leukemia B. Acute Myeloblastic Leukemia C. Chronic Lymphocytic Leukemia D. Chronic Myeloid Leukemia
    1 Mark

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