RGUHS MBBS Pathology November 2025 (1027 CBME)

1027Rajiv Gandhi University of Health Sciences · Pathology · 2025 · November · CBME

Questions (30)

1.A middle-aged female presented with migratory polyarthritis, weak heart sound, tachycardia, pericardial friction rub following recurrent attacks of Pharyngitis. a) What is your diagnosis? b) Describe the pathophysiology and morphology of this condition. c) List the complications associated with this condition
10 Marks
2.A 50-year-old postmenopausal woman presented with hard lump of 8x8 cm in the lower outer quadrant of left breast. Fine needle aspiration cytology showed groups and clusters of ductal epithelial cells with cellular and nuclear atypia. a) What is your diagnosis? b) Discuss the morphology and list the types of the above condition. c) Enumerate the prognostic factors of the disease.
10 Marks
3.Differences between Ulcerative colitis and Crohn’s disease
5 Marks
4.Discuss the gross, microscopy, X ray appearance of Osteoclastoma
5 Marks
5.Describe the etiopathogenesis and morphological types of Emphysema
5 Marks
6.Describe the pathogenesis and morphological findings in Hashimoto’s thyroiditis
5 Marks
7.Describe the etiopathogenesis and complications of Acute Pyelonephritis
5 Marks
8.Describe the morphology of acute and chronic hepatitis. Add a note on outcome of chronic hepatitis
5 Marks
9.Cryptorchidism
5 Marks
10.Endometriosis
5 Marks
11.Krukenberg tumor
3 Marks
12.Gout
3 Marks
13.Pheochromocytoma
3 Marks
14.Basal cell carcinoma
3 Marks
15.Enumerate the glial neoplasms of brain
3 Marks
16.Warthin’s tumour
3 Marks
17.Diabetic kidney
3 Marks
18.List the complications associated with lung cancer
3 Marks
19.Types of Reed Sternberg Cells
3 Marks
20.Complications of cirrhosis
3 Marks
21.Which of the following is most reliable feature of malignant transformation of pheochromocytoma? A. Presence of mitotic figures B. Presence of metastasis to other organs C. Vascular/ capsular invasion D. All of the above
1 Mark
22.A pediatrician performing an ophthalmoscopic examination on a four-year-old boy, notices several small pigmented nodules in his irises. He also notices six light brown macules on the trunk of the child of variable sizes. This boy may have a propensity to develop tumors in which of the following structures? A. Bladder B. Colon C. Peripheral nerve D. Skin
1 Mark
23.Paget’s disease of the bone is also called A. Osteitis deformans B. Brittle bone disease C. Fibrous dysplasia D. Osteomalacia
1 Mark
24.Hematuria with red cell cast and dysmorphic RBC are seen in: A. Acute glomerulonephritis B. Renal TB C. Renal Calculi D. Chronic renal failure
1 Mark
25.Inflammatory Causes of pleural effusion include all EXCEPT A. Tuberculosis B. Bronchiectasis C. Lung infarct D. Renal failure
1 Mark
26.Choriocarcinoma is characterized by all EXCEPT A. Primarily trophoblastic tumor B. It can occur following hydatidiform mole C. Villi present D. It can metastasize to lungs
1 Mark
27.In an individual with suspected myocardial infarction of 24 hours duration, the serum enzyme estimation of choice is A. Lactate dehydrogenase B. Myoglobin C. Creatine phosphokinase-MB D. Oxaloacetate transaminase
1 Mark
28.Myasthenia gravis is associated with A. Hypergammaglobulinemia B. Thymoma C. Squamous cell carcinoma D. Hepatic adenoma
1 Mark
29.Chronic ulcerative colitis usually starts in the: A. Hepatic or splenic flexure B. Rectosigmoid area C. Transverse colon D. Terminal ileum
1 Mark
30.Conjugated hyperbilirubinemia results from A. Gilberts jaundice B. Dubin Johnson syndrome C. Physiological jaundice D. Decreased hepatic uptake
1 Mark

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