RGUHS MBBS Pharmacology December 2024 (1028 CBME)

1028Rajiv Gandhi University of Health Sciences · Pharmacology · 2024 · December · CBME

Questions (30)

1.Define Bioavailability. Discuss the factors affecting bioavailability of a drug administered orally.
10 Marks
2.A forty-five-year-old farmer was brought to the hospital with breathlessness, lacrimation, bowel and bladder incontinence. A diagnosis of Organophosphorous poisoning was made. a) Outline the management of this patient. b) Mention the specific antidotes useful in this patient and explain the rationale of using them
10 Marks
3.What is microsomal enzyme induction? Explain its consequences with any two examples
5 Marks
4.Mention any three Atropine substitutes and explain their therapeutic uses
5 Marks
5.Write the mechanism of action and therapeutic uses of Benzodiazepines
5 Marks
6.Write the mechanism of action, adverse effects and therapeutic uses of Sodium Valproate
5 Marks
7.Discuss the various techniques of local anaesthesia
5 Marks
8.A 25-year-old computer engineer presents with episodes of unilateral pulsatile headache preceded by photophobia and vomiting for the past few months. A diagnosis of Migraine was made. She was prescribed Sumatriptan. Explain the mechanism of action and contraindications for Triptans
5 Marks
9.A 52-year-old lady, a known asthmatic presents to the hospital with acute breathlessness and wheeze. A diagnosis of Status asthmaticus (Acute severe asthma) was made. Discuss the pharmacotherapy of Status asthmaticus (Acute severe asthma)
5 Marks
10.Write the mechanism of action and therapeutic uses of Omeprazole
5 Marks
11.What is Teratogenicity? Mention two drugs causing teratogenicity with their teratogenic effects
3 Marks
12.List three classes of drugs with a suitable example for each used in Chronic simple (open angle) Glaucoma
3 Marks
13.Write three advantages of Selective serotonin reuptake inhibitors over Tricyclic antidepressants
3 Marks
14.Write the rationale of using Morphine in acute left ventricular failure
3 Marks
15.Aspirin causes gastric mucosal damage. Explain
3 Marks
16.Name three Antitussives
3 Marks
17.Rationale of using Ondansetron in cancer chemotherapy induced vomiting
3 Marks
18.Mention three advantages of Halothane as general anaesthetic agent
3 Marks
19.Name three drugs obtained from plant sources
3 Marks
20.List three uses of Dimercaprol
3 Marks
21.The therapeutic index of a drug indicates its A. Safety B. Efficacy C. Potency D. All of the above
1 Mark
22.Which of the following drug undergoes Hofmann elimination? A. Atracurium B. Pancuronium C. Vecuronium D. Rocuronium
1 Mark
23.The mydriatic with quickest and briefest action is A. Atropine B. Homatropine C. Cyclopentolate D. Tropicamide
1 Mark
24.Ethanol is administered in methanol poisoning to A. Correct acidosis caused by formic acid B. Prevent seizures due to methanol C. Compete with methanol for alcohol dehydrogenase D. Increase generation of formaldehyde
1 Mark
25.The agent which can reverse the sedative action of Benzodiazepines is A. Caffeine B. Doxapram C. Acetyl cysteine D. Flumazenil
1 Mark
26.The standard drug therapy for Parkinson’s disease is A. Pyridoxine B. Dopamine C. Levodopa + Carbidopa D. Dopamine + Pyridoxine
1 Mark
27.The prostaglandin analogue used in Peptic ulcer disease is A. Misoprostol B. Carboprost C. Latanoprost D. Travoprost
1 Mark
28.The class of drug NOT used in the treatment of bronchial asthma is A. Beta 2 agonists B. Corticosteroids C. Methylxanthines D. Cholinesterase inhibitors
1 Mark
29.Oral rehydration therapy has one of the following beneficial effects A. Stops diarrhoea B. Restores hydration and electrolyte balance C. Hastens the clearance of enteropathogens D. Avoids the need for specific antimicrobial therapy
1 Mark
30.Drug used in treatment of scorpion sting is A. Pralidoxime B. Pramipexole C. Prazosin D. Propylthiouracil
1 Mark

Pharmacology question papers & analysis

Previous-year question paper.More papers →Report an issue

Questions (30)

More from Pharmacology

Pharmacology question papers & analysis