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RGUHS MBBS Pharmacology April 2025 (1028 CBME)

1028Rajiv Gandhi University of Health Sciences · Pharmacology · 2025 · April · CBME

Questions (30)

  1. 1.Define Bioavailability. Discuss various factors that affect Bioavailability
    10 Marks
  2. 2.A 22 year old unresponsive and unconscious man is brought to hospital. His heart rate is 60 per minute, blood pressure is 90/60 mm of Hg and respiratory rate is 10 per minute. He has pinpoint pupils. The treating doctor made a diagnosis of Morphine poisoning. a) Write the drug treatment for Morphine poisoning b) Write the central nervous system actions, therapeutic uses and adverse effects of morphine
    10 Marks
  3. 3.Adverse effects and contraindications of beta blockers
    5 Marks
  4. 4.Methods of prolonging drug action
    5 Marks
  5. 5.Discuss the management of organophosphorous Poisoning
    5 Marks
  6. 6.Therapeutic uses of atropine substitutes
    5 Marks
  7. 7.Disease Modifying Anti-Rheumatoid Drugs (DMARDs)
    5 Marks
  8. 8.Inhalational glucocorticoids used in Bronchial Asthma
    5 Marks
  9. 9.A 40 year old businessman presents with complaints of dyspepsia and epigastric pain. Endoscopy revealed Peptic ulcer. He was prescribed pantoprazole. a) Explain the rationale of using pantoprazole in this patient. b) Write its uses and adverse effects
    5 Marks
  10. 10.A 45 year old man presents with sad mood, low energy and loss of interest and pleasure. The psychiatrist diagnosed him to be suffering from depression and prescribed Fluoxetine. a) Explain the rationale of using fluoxetine in this patient. b) Write its other therapeutic uses and adverse effects.
    5 Marks
  11. 11.Explain the term first order kinetics with an example
    3 Marks
  12. 12.Rationale of using latanoprost in Glaucoma
    3 Marks
  13. 13.What is diffusion Hypoxia? How is it prevented?
    3 Marks
  14. 14.Explain the rationale of using Diazepam in Insomnia
    3 Marks
  15. 15.Rationale of combining Lignocaine with Adrenaline
    3 Marks
  16. 16.Mention three disadvantages of using Liquid Paraffin as a Purgative
    3 Marks
  17. 17.Rationale of using Paracetamol in fever
    3 Marks
  18. 18.Write three mucolytics
    3 Marks
  19. 19.Explain the concept of Essential medicines (drugs)
    3 Marks
  20. 20.Write three uses of d-Penicillamine
    3 Marks
  21. 21.Which of the following receptor is located intracellularly A. Opioid receptor B. Steroid receptor C. Dopamine receptor D. GABA receptor
    1 Mark
  22. 22.Nicotinic receptor is A. Ligand gated ion channel B. G protein coupled C. Tyrosine kinase linked D. Intra-cellular
    1 Mark
  23. 23.Propranolol is avoided in which one of the following conditions A. Hypertension B. Ischemic heart disease C. Cardiac arrhythmias D. Bronchial asthma
    1 Mark
  24. 24.Which of the following is a prodrug of adrenaline used in glaucoma A. Brimonidine B. Dipivefrine C. Phenylephrine D. Pilocarpine
    1 Mark
  25. 25.The drug useful in the treatment of trigeminal neuralgia is A. Paracetamol B. Carbamazepine C. Aspirin D. Morphine
    1 Mark
  26. 26.Prolonged treatment with Lithium can cause A. Diabetes mellitus B. Goitre C. Gout D. Rheumatoid arthritis
    1 Mark
  27. 27.A 35 year old woman is suffering from severe migraine. The migraine gets relieved by sumatriptan. Which drug is appropriate for prophylaxis of migraine? A. Dihydroergotamine B. Ibuprofen C. Propranolol D. Paracetamol
    1 Mark
  28. 28.Dextromethorphan is an A. Analgesic B. Antitussive C. Expectorant D. Antihistaminic
    1 Mark
  29. 29.Which antiemetic is used to inhibit levodopa induced vomiting without blocking its antiparkinsonian effect A. Dicyclomine B. Domperidone C. Itopride D. Ondansetron
    1 Mark
  30. 30.An Orphan Drug is A. Low cost drug B. Inert drug C. Drug for rare disease/condition D. An essential drug
    1 Mark

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