RGUHS MBBS Pharmacology May 2023 (1029 CBME)

1029Rajiv Gandhi University of Health Sciences · Pharmacology · 2023 · May · CBME

Questions (30)

1.a) Classify Antihypertensive drugs. b) Discuss the cardiovascular actions of Calcium channel Blockers c) Enumerate the Uses of Calcium channel blockers
10 Marks
2.A 20 year old male reported to a hospital with fever, accompanied by chills and rigors, headache and fatigue. Blood smear examination shows presence of plasmodium Falciparum parasite. A diagnosis of //Falciparum// Flaciparum Malaria was made. a) Classify Antimalarial drugs b) Describe the mechanism of action, uses and adverse effects of Chloroquine
10 Marks
3.Mechanism of action and Adverse effects cyclophosphamide
5 Marks
4.A 34 year old woman is suffering from urinary tract infection. Urine culture report shows E. Coli infection which is sensitive to gentamicin a) Explain the mechanism of action of gentamicin b) Mention the adverse effects of gentamicin
5 Marks
5.Mechanism of action, Uses and adverse effects Bisphosphonates
5 Marks
6.Mechanism of action and Adverse effects of Sulphonylureas
5 Marks
7.Enumerate the therapeutic uses and Adverse effects of glucocorticoids
5 Marks
8.A married 28 year old lady having a 4 year old child is requesting for Oral contraceptive pill. Which type of oral contraceptive pill will you prescribe? What are the contraindications and adverse effects of oral contraceptive pills?
5 Marks
9.Mechanism of action, uses and adverse effects of Warfarin
5 Marks
10.Mention Four Thiazide diuretics. Enumerate the uses and adverse effects of thiazide diuretics?
5 Marks
11.Rationale of using Angiotensin converting enzyme Inhibitors (ACE Inhibitors) in Heart failure?
3 Marks
12.Name Three vitamin D preparations
3 Marks
13.Define chemoprophylaxis. Give two example
3 Marks
14.List three fibrates used as hypolipidemic agents
3 Marks
15.What is the rationale of using Metronidazole in Pseudomembranous enterocolitis
3 Marks
16.Mention three protease inhibitors used in HIV infection
3 Marks
17.Short course chemotherapy regimen for a newly diagnosed drug sensitive pulmonary tuberculosis
3 Marks
18.Rationale of combining Piperacillin with Tazobactum
3 Marks
19.Explain why orally administered Vit B12 is not effective in pernicious anemia
3 Marks
20.Write Three uses of Ivermectin
3 Marks
21.All the following drugs are used for treatment of Hypertensive emergencies EXCEPT A. Sodium Nitroprusside B. Esmolol C. Glyceryl Trinitrate D. Adrenaline
1 Mark
22.Which of the following is an adverse effect streptokinase A. Bleeding B. Infection C. Respiratory Failure D. Alopecia
1 Mark
23.Propranolol is a suitable antihypertensive in patients with co-existing A. Anxiety B. Peripheral vascular disease C. Bronchial Asthma D. Decompensated Heart failure
1 Mark
24.Tranexamic acid is used to control bleeding in A. Epistaxis B. Heart Failure C. Bronchial Asthma D. Pneumonia
1 Mark
25.Prostaglandin analogue useful in the treatment of postpartum haemorrhage is A. Carboprost B. Latanoprost C. Alprostadil D. Epoprostenol
1 Mark
26.Indication for Octreotide is A. Crohn's disease B. Irritable bowel syndrome C. Esophageal variceal bleeding D. Ulcerative Colitis
1 Mark
27.Which of the following inhibits bacterial cell wall synthesis? A. Vancomycin B. Tetracyclines C. Erythromycin D. Streptomycin
1 Mark
28.Combined use of Antimicrobials is indicated in all of the following conditions EXCEPT A. Ascariasis B. Leprosy C. HIV D. Tuberculosis
1 Mark
29.Oral vancomycin is indicated in the following condition A. Tuberculosis B. Typhoid C. Malaria D. MRSA infection
1 Mark
30.Which antileprotic drug is indicated in lepra reaction A. Dapsone B. Rifampin C. Clofazimine D. Minocycline
1 Mark

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