apyqace

RGUHS MBBS Pharmacology February 2024 (1029 CBME)

1029Rajiv Gandhi University of Health Sciences · Pharmacology · 2024 · February · CBME

Questions (30)

  1. 1.A 52 year old obese male attended endocrinology department with polyuria, polyphagia, polydipsia and generalized weakness. His random blood sugar is 200 mg%, HbA1c is 8%. He is not on any other medication. He was diagnosed to be suffering from Type-2 diabetes mellitus a) Classify Oral Antidiabetic drugs with suitable examples b) Explain the mechanism of action and enumerate the adverse effects of Metformin c) Outline the drug treatment of Diabetic Ketoacidosis
    10 Marks
  2. 2.a) Classify the drugs used in the treatment of Tuberculosis with examples b) Describe the mechanism of action, therapeutic uses, adverse effects of Rifampicin
    10 Marks
  3. 3.A 53 year old man presented with complaints of chest tightness and pain while climbing stairs, relieved after rest. A diagnosis of exertional angina was made. He was prescribed glyceryl trinitrate. a) Explain the mechanism of action of glyceryl trinitrate in angina pectoris b) What are the adverse effects of glyceryl trinitrate?
    5 Marks
  4. 4.Mention any three groups of antiplatelet agents giving an example for each. Mention the uses of antiplatelet drugs
    5 Marks
  5. 5.A 65 year old patient presented with headache, giddiness and palpitations. He had no other neurological symptoms. His Blood pressure was 280/148 mm of Hg. Discuss the drug treatment of hypertensive emergencies
    5 Marks
  6. 6.Mechanism of action, precautions and Uses of Radioactive Iodine
    5 Marks
  7. 7.Discuss HAART (Highly active anti retroviral therapy)
    5 Marks
  8. 8.Mechanism of action, Therapeutic uses and Adverse effects of Cyclosporine
    5 Marks
  9. 9.Mechanism of action and Therapeutic uses of Potassium sparing Diuretics
    5 Marks
  10. 10.Mechanism of action, Uses and Adverse effects of Clomiphene citrate
    5 Marks
  11. 11.Name three live attenuated vaccines
    3 Marks
  12. 12.Rationale for combining Amoxicillin with Clavulanic acid
    3 Marks
  13. 13.Name two statins. Why is statin not combined with fibrates?
    3 Marks
  14. 14.Three contraindications for the use of Enalapril
    3 Marks
  15. 15.Three drugs used in Choloroquine resistant falciparum malaria
    3 Marks
  16. 16.Mention three general toxicities of Aminoglycoside antibiotics
    3 Marks
  17. 17.Rationale of using Digoxin in heart failure
    3 Marks
  18. 18.Mention three measures to be taken to prevent the development of antimicrobial drug resistance
    3 Marks
  19. 19.What are advantages of Liposomal Amphotericin–B?
    3 Marks
  20. 20.What is Pseudomembranous enterocolitis? Name Two drugs used for its treatment.
    3 Marks
  21. 21.Which of the following drug is a direct renin inhibitor used as an antihypertensive A. Atenolol B. Aliskerin C. Amiloride D. Amlodipine
    1 Mark
  22. 22.All of the following combinations are used to treat Hypertension EXCEPT A. Amlodipine + Lisinopril B. Lisinopril + Hydrochlorthiazide C. Losartan + Amlodipine D. Verapamil+ Propranolol
    1 Mark
  23. 23.The drug useful in treating Biliary colic is A. Neostigmine B. Pilocarpine C. Nitroglycerine D. Physostigmine
    1 Mark
  24. 24.Primary indication for Recombinant human erythropoietin is A. Pulmonary embolism B. Coronary artery disease C. Deep vein thrombosis D. Chronic renal failure
    1 Mark
  25. 25.Which of the following oral antidiabetic drug inhibits enzyme Dipeptidyl peptidase- 4 A. Metformin B. Glimeperide C. Acarbose D. Vildagliptin
    1 Mark
  26. 26.Indication for Tamoxifen citrate is A. Female infertility B. Endometrial carcinoma C. Carcinoma breast D. Deep vein thrombosis
    1 Mark
  27. 27.Which of the following is a common property of Aminoglycoside antibiotics? A. They are primarily active against aerobic gram negative bacilli B. They are more active in acidic medium C. They are all absorbed orally D. They are completely metabolized in liver
    1 Mark
  28. 28.‘Red man syndrome’ is associated with rapid intravenous injection of the following antibiotic A. Vancomycin B. Clindamycin C. Cefoperazone D. Piperacillin
    1 Mark
  29. 29.The drug of choice for tropical eosinophilia is A. Carbamazepine B. Diethylcarbamazine C. Carbimazole D. Clomiphene citrate
    1 Mark
  30. 30.Orally effective drug in scabies is A. Permethrin B. Ivermectin C. Benzoyl peroxide D. Crotamiton
    1 Mark

More from Pharmacology

Pharmacology question papers & analysis

Previous-year question paper.More papers →Report an issue
Question content is not available for printing. View it at pyqace.com