KNRUHS MBBS Biochemistry November 2024 (MB2019101 Regular)

MB2019101Kaloji Narayana Rao University of Health Sciences · Biochemistry · 2024 · November · Regular

Questions (25)

1.Na+ -K+ ATPase is the marker enzyme of a) Nucleus b) Plasma Membrane c) Golgi Bodies d) Cytosol
1 Mark
2.Who proposed Fluid Mosaic model of Cell Membrane in 1972 a) Darson and Singer b) Frye and Edidin c) Brown and Goldstein d) Singer and Nicholson
1 Mark
3.Eicosanoids includes a) Prostaglandins b) Leukotrienes c) Thromboxane’s d) All of the above
1 Mark
4.Which of the following is cardio protective fatty acid a) Palmitic acid b) Stearic acid c) Propionic acid d) Omega 3 fatty acid
1 Mark
5.Suicidal enzyme is a) Lipoxygenase b) Cyclooxygenase c) Thromboxane synthase d) 5- Nucleosidase
1 Mark
6.Cystic fibrosis results from defective ion channels for a) NA+ b) K+ c) Cl- d) H+
1 Mark
7.Sphingomyelinase deficiency seen in a) Niemann-Pick disease b) Gaucher’s disease c) Tay-Sach’s disease d) Guillain Barre syndrome
1 Mark
8.The SDA (Specific Dynamic Action) is the highest for the following nutrient a) Proteins b) Fats c) Vitamins d) Carbohydrates
1 Mark
9.Renal rickets is caused by a) Decreased formation of Cholecalciferol b) Increased synthesis of 25- HCC c) Decreased synthesis of calcitriol d) None of the above
1 Mark
10.Daily requirement of Iodine for an adult is a) 15-20μg b) 150-200μg c) 800-900μg d) 600-700μg
1 Mark
11.A 50-year-old obese male came to causality with complaints of severe chest pain and breathlessness. He is a known diabetic since 6 years on irregular treatment. His ECG revealed an ST segment elevation. His lipid profile showed the following. T. cholesterol- 320 mg%, LDL cholesterol- 180 mg%, HDL cholesterol- 24 mg%, Triglycerides- 250 mg% a) What is the probable diagnosis. b) Explain in detail the steps involved in synthesis of cholesterol in our body. c) Causes for hypercholesterolemia. d) Role of statins to reduce the cholesterol.
15 Marks
12.a) What is Gluconeogenesis. b) Under what conditions is the process of gluconeogenesis activated in the body. c) What are the substances for gluconeogenesis. d) Mention the key enzymes and how is alanine converted to glucose. e) Justify the statement: Gluconeogenesis is not a simple reversal of glycolysis.
15 Marks
13.What are the differences between competitive and noncompetitive inhibition. Give two examples for competitive inhibition.
6 Marks
14.How the Physician becomes a part of Health Care System.
6 Marks
15.Write in detail on the Protein-Energy malnutrition disorders.
6 Marks
16.Describe the principle and applications of electrophoresis.
6 Marks
17.Describe the sources, daily requirements and functions of Vitamin D.
6 Marks
18.Describe transport mechanisms across the cell membrane.
6 Marks
19.Discuss in detail on the inhibitors of ETC and oxidative phosphorylation and a note on inherited disorders of oxidative phosphorylation.
6 Marks
20.Essential fatty acids.
3 Marks
21.What is an allosteric enzyme. And give one example of reaction catalysed by an allosteric enzyme.
3 Marks
22.Explain the concept: “HMP pathway is significant in preservation of erythrocyte membrane integrity”.
3 Marks
23.Lipotropic factors.
3 Marks
24.Mention the sources and functions of Iron.
3 Marks
25.Mention the dietary importance of Proteins.
3 Marks

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