KNRUHS MBBS Biochemistry November 2025 (MB2019101 Regular)

MB2019101Kaloji Narayana Rao University of Health Sciences · Biochemistry · 2025 · November · Regular

Questions (25)

  1. 1.Calcitriol acts synergistically with the following hormone on bone a) Calcitonin b) Epinephrine c) Parathyroid hormone (PTH) d) Insulin
    1 Mark
  2. 2.Coenzyme A is derived from which vitamin a) Thiamine b) Pyridoxine c) Cobalamin d) Pantothenate
    1 Mark
  3. 3.Which one of the following trace element deficiency causes loss of taste sensation a) Copper b) Iron c) Zinc d) Selenium
    1 Mark
  4. 4.Which of the following nonproteins can act as an enzyme. a) DNA b) RNA c) Phospholipid d) Glycolipid
    1 Mark
  5. 5.Thermogenin is found in a) Thyroid Gland b) Thymus Gland c) Brown Adipose Tissue d) Adrenal Gland
    1 Mark
  6. 6.Anticoagulants used in biochemical tests are a) Heparin b) EDTA c) Potassium or Sodium oxalate d) All of the above
    1 Mark
  7. 7.Insulin /Glucagon ratio is high in the a) Well-fed state b) Overnight fast c) Early fasting state d) All the above
    1 Mark
  8. 8.In the well fed state, all the following pathways are active in the liver, except a) Glycolysis b) Glucose uptake by hepatocytes c) Gluconeogenesis d) Glycogenesis
    1 Mark
  9. 9.Earliest Marker of myocardial Infarction is a) Ck1 b) Ck2 c) Ck3 d) Ck4
    1 Mark
  10. 10.Antidote kits for cyanide poisoning contain a) Amyl nitrate b) Sodium nitrite c) BAL d) Both A and B
    1 Mark
  11. 11.A 6-year-old was brought to OPD with a history of slow growth and pain in bones. On examination revealed bow leg deformities; frontal bossing; pigeon chest deformities. Laboratory investigations shows:- Serum Calcium = 7.9mg%, Serum Phosphorus = 2.4mg%, Serum alkaline phosphatase = 690U/L. a) What is the likely diagnosis? b) Write in detail about dietary sources, daily requirement, biochemical functions, regulation of blood calcium homoeostasis and diseased conditions of the deficient mineral element. c) Write the normal levels of the above lab tests in serum.
    15 Marks
  12. 12.a) Classify the Enzymes? Giving one example for each. b) What are factors influencing enzyme activity? c) What are the different types of enzyme inhibition. Explain with suitable examples. d) Clinical importance of inhibition.
    15 Marks
  13. 13.Polymerase chain reaction (PCR) and its clinical application. What is RTPCR?
    6 Marks
  14. 14.What are the sources of Dietary fibre? Discuss the importance of it in Nutrition.
    6 Marks
  15. 15.Schematic representation of Electron transport chain. Add a note on Uncouplers.
    6 Marks
  16. 16.Describe how physician is important in health care system?
    6 Marks
  17. 17.Define BMR. What are the factors regulating BMR.
    6 Marks
  18. 18.Describe in detail on the metabolism of Galactose and add a note on disorders of it correlating clinically.
    6 Marks
  19. 19.Outline the Denovo synthesis of fatty acid. What are the advantages of having a multifunctional enzyme complex?
    6 Marks
  20. 20.Glycated Haemoglobin & its clinical interpretation.
    3 Marks
  21. 21.Fluid mosaic model of membrane.
    3 Marks
  22. 22.Benedict’s test.
    3 Marks
  23. 23.Hetero polysaccharides.
    3 Marks
  24. 24.Write on the classification and characteristics of Hyper and Hypolipoproteinaemia’s.
    3 Marks
  25. 25.Wernicke – Korsakoff syndrome.
    3 Marks

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