KNRUHS MBBS Biochemistry September 2025 (MB2019101 Regular)

MB2019101Kaloji Narayana Rao University of Health Sciences · Biochemistry · 2025 · September · Regular

Questions (25)

1.Which one of the following statement is correct regarding HDL ( High density lipoprotein ) a) It transport dietary lipids from the intestine to various tissues b) It transports endogenous lipids from the liver to the peripheral tissues c) It transports cholesterol from the peripheral tissues to the liver d) It transports the fatty acids released by lipolysis
1 Mark
2.During starvation, the brain derives most of its energy needs by utilizing the following a) Fatty acids b) Ketone bodies c) Amino acids d) Glucose
1 Mark
3.Enzymes catalyzing electron transport are present mainly in the a) Ribosomes b) Endoplasmic reticulum c) Lysosomes d) Inner mitochondrial membrane
1 Mark
4.The carbohydrate of the blood group substances is a) Sucrose b) Fucose c) Arabinose d) Maltose
1 Mark
5.Fluoride inhibits_____and arrests glycolysis. a) Glyceraldehyde-3-phosphate dehydrogenase b) Aconitase c) Enolose d) Succinate DH
1 Mark
6.All the following statements about carnitine are true except a) It can be synthesized in the human body b) It can be synthesized from methionine and lysine c) It is required for transport of short chain fatty acids into mitochondria d) Its deficiency can occur due to haemodialysis
1 Mark
7.Lieberman-Burchard reaction is performed to detect a) Cholesterol b) Glycerol c) Fatty acid d) Vitamin D
1 Mark
8.The active form of vitamin D is a) 1, 25 —DHCC b) 1,24 — DHCC c) 24,25 — DHCC d) 25- HCC
1 Mark
9.Kwashiorkor occurs when the diet is severely deficient in a) Iron b) Calories c) Proteins d) Essential fatty acids
1 Mark
10.Keshan disease occurs due to the deficiency of a) Selenium b) Chromium c) Cobalt d) Manganese
1 Mark
11.A 60-year-old male presented with acute chest pain of ½ hour duration. His past history reveals as a known diabetic; known hypertensive, known smoker and known alcoholic. The biochemical analysis are as follows: Blood glucose = 380 mg%, Serum cholesterol = 300 mg% AST = 60 U/L, ALT= 15 U/L, CPK & LDH were elevated. a) Give your provisional diagnosis and meaning of it. b) Explain in detail about cardiac markers with graph patterns. c) What are the other markers which can be estimated in this case. d) Write the normal values of all of the above lab tests.
15 Marks
12.12.Write in detail on the metabolism of Iron- the essential trace element in the following headings a) What are the other essential trace elements, name them? b) Describe the dietary source, daily requirement, factors affecting ‘Fe’ absorption, transport, storage, biochemical functions and deficiency manifestations of the mineral. c) Specially explain the mucosal block theory of Iron absorption to support the statement – Iron is a one-way element.
15 Marks
13.Write about the structural and functional organization of electron transport chain. Add a note on inhibitors of it.
6 Marks
14.Write about Ketone body’s synthesis and discuss the importance.
6 Marks
15.Describe the role of a physician in health care system
6 Marks
16.Discuss in detail on the regulation of blood glucose level (Homeostasis of blood glucose level) and define hypoglycaemia. Write in detail on various causes of Hypoglycaemia.
6 Marks
17.Define phospholipids. State their function and importance.
6 Marks
18.Write in detail on the biochemical function, RDA, and deficiency manifestations of Vitamin A.
6 Marks
19.Discuss in detail on the transport mechanisms/process across the cell membranes.
6 Marks
20.What is the principle, procedure and clinical application of radio immunoassay.
3 Marks
21.Mention biological active form of folic acid. How is it involved in one carbon metabolism?
3 Marks
22.Polysaccharides.
3 Marks
23.Vitamin K cycle – biochemical function of vitamin K.
3 Marks
24.Glycogen storage disorders.
3 Marks
25.Biochemical function of selenium.
3 Marks

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