KNRUHS MBBS Biochemistry September 2025 (MB2019102 Regular)

MB2019102Kaloji Narayana Rao University of Health Sciences · Biochemistry · 2025 · September · Regular

Questions (25)

1.Pulses are deficient in a) Lysine b) Threonine c) Methionine d) Tryptophan
1 Mark
2.Which one of the following theories effectively explains the feature of immune response? a) Selection theory b) Germ line theory c) Template theory d) Clonal selection theory
1 Mark
3.Chronic obstructive airway disease results in a) Respiratory acidosis b) Metabolic acidosis c) Respiratory alkalosis d) Metabolic alkalosis
1 Mark
4.A hormone secreted from anterior pituitary is a) Growth hormone b) Vasopressin c) Oxytocin d) Epinephrine
1 Mark
5.Molecules involved in immune response are a) MHC molecules b) Cytokines c) Chemokines d) All the above
1 Mark
6.Antioxidant enzymes are a) Superoxide dismutase (SOD) b) Catalase c) Glutathione peroxidase d) All the above
1 Mark
7.Biotransformation takes place in a) Intestines b) Lungs c) Skin d) Liver
1 Mark
8.Serum acid phosphatase level increases in a) Carcinoma of Prostate b) Carcinoma of Lung c) Carcinoma of Liver d) Carcinoma of Oesophagus
1 Mark
9.The predominant buffer system of plasma is the a) Albumin buffer b) Bicarbonate buffer c) Haemoglobin buffer d) Phosphate buffer
1 Mark
10.The Peptide that protects RBC membrane is a) Oxytocin b) Glutathione c) Vasopressin d) Angiotensin
1 Mark
11.Discuss the metabolism of Glycine. Give an account on biological important compounds synthesised from Glycine. Add a note on primary Hyperoxaluria.
15 Marks
12.A 45-year-old obese lady presented to the causality with complaints of acute right upper abdominal pain, mild fever, loss of appetite and generalized itching. On further questioning, she gave history of frothy, clay coloured stool and high coloured urine. a) What is the probable diagnosis? b) Mention the laboratory tests you advise to confirm the diagnosis? c) Describe the normal bilirubin metabolism. d) How do you relate the high coloured urine, itching and clay-coloured stools with altered metabolic pathway of bilirubin in this condition.
15 Marks
13.Describe the Oncogenes and their role in Cancer with examples.
6 Marks
14.Discuss the Renal mechanisms involved in regulation of blood pH.
6 Marks
15.Recombinant DNA technology and its applications.
6 Marks
16.What are your perspectives on lifelong learning by Physician?
6 Marks
17.Discuss the structure of normal Haemoglobin. Add a note on haemoglobin derivatives.
6 Marks
18.What is Transamination and its significance? List two Transaminases.
6 Marks
19.Structure and functions of t-RNA.
6 Marks
20.DNA polymerase.
3 Marks
21.Alkaptonuria.
3 Marks
22.What is the normal anion gap? State its importance.
3 Marks
23.Phase II detoxification.
3 Marks
24.Point mutation.
3 Marks
25.Porphyria Cutanea tarda.
3 Marks

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