KUHS MBBS Biochemistry Previous Question Paper - May 2022 (115001 2019 Scheme)

115001Kerala University of Health Sciences · Biochemistry · 2022 · May · 2019 Scheme

Questions (22)

1.A 45-year-old man complaints of increased appetite, thirst, and frequent micturition. His random blood sugar is 346 mg/dl • What is the diagnosis. What are the diagnostic criteria • Discuss the relevant investigations that can be done for further monitoring of the patient • How is blood glucose regulated • What is the renal threshold for Glucose
15 Marks
2.Define Beta oxidation. Enumerate the steps and add a note on its regulation. Explain the energetics for palmitic acid
15 Marks
3.Enumerate the steps of TCA cycle. Add a note on malate shuttle
8 Marks
4.Describe the salient features of any two types of enzyme inhibition with suitable examples
8 Marks
5.Define nitrogen balance. Add a note on the clinical conditions altering nitrogen balance
8 Marks
6.Discuss the catabolism of heme. Describe the causes and laboratory finding in obstructive jaundice
8 Marks
7.What are the sources of vitamin A. Enumerate the biochemical role and deficiency manifestations of vitamin A
8 Marks
8.Define Peptide bonds. Enumerate two biochemically important peptides and their significance.
4 Marks
9.Substrate level phosphorylation
4 Marks
10.Golgi complex
4 Marks
11.Discuss the formation of melanin and add a note on albinism
4 Marks
12.Describe the synthesis of any two compounds of biomedical importance synthesized from glycine
4 Marks
13.Why is sucrose a non reducing sugar
1 Mark
14.Enzyme defect in Alkaptonuria
1 Mark
15.Name two cardiac markers
1 Mark
16.Name two prostaglandins and mention their importance
1 Mark
17.Enzyme defect in Von-Gierke’s disease
1 Mark
18.Give the normal reference range for • Serum triglyceride • Serum creatinine
1 Mark
19.Marker enzyme for mitochondria
1 Mark
20.Name two compounds formed from Tryptophan
1 Mark
21.Name the enzyme activity to assess the deficiency of vitamin B₁
1 Mark
22.Name the rate limiting enzyme of heme synthesis.
1 Mark

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