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KUHS MBBS Biochemistry Previous Question Paper - February 2023 (115001 2019 Scheme)

115001Kerala University of Health Sciences · Biochemistry · 2023 · February · 2019 Scheme

Questions (22)

  1. 1.Mother noticed that her child didn’t attain milestones for the age. Mother also noticed hypopigmentation and mousy odour a) Name the amino acid involved b) What is the diagnosis c) What is the metabolism of the amino acid. Mention the inborn errors associated with its metabolism. d) Enumerate the laboratory investigations aiding in the diagnosis. e) Name two specialized compounds formed from tyrosine and discuss their formation in brief
    15 Marks
  2. 2.Define Enzyme, what are the factors affecting enzyme activity. Explain various mechanism of enzyme regulation.
    15 Marks
  3. 3.How are lipids digested and absorbed. Add a note on the associated disorders
    8 Marks
  4. 4.Explain glycolysis, regulation and its energetics
    8 Marks
  5. 5.What is thalassemia. Discuss the clinical features, molecular basis and laboratory diagnosis of thalassemia
    8 Marks
  6. 6.Define dietary fibres. Give suitable examples and their biomedical importance.
    8 Marks
  7. 7.Explain electron transport chain with a suitable diagram. Add a note on the inhibitors of ETC
    8 Marks
  8. 8.Enumerate the sources, daily requirement and deficiency manifestation of vitamin C.
    4 Marks
  9. 9.Kwashiorkor
    4 Marks
  10. 10.Hypoglycemia
    4 Marks
  11. 11.Mitochondria
    4 Marks
  12. 12.Name four therapeutically important enzymes and their significance
    4 Marks
  13. 13.Name two metabolites of biochemical importance formed in HMP pathway
    1 Mark
  14. 14.Isoelectric pH of albumin
    1 Mark
  15. 15.Name the essential fatty acids
    1 Mark
  16. 16.Name two non-carbohydrates which give a positive Benedict’s test
    1 Mark
  17. 17.Name a non-glycerol containing phospholipid and mention its significance.
    1 Mark
  18. 18.Enzyme defect in MSUD.
    1 Mark
  19. 19.Give the normal reference range for • Fasting Blood Glucose • Serum cholesterol
    1 Mark
  20. 20.Name two specialized compounds derived from glycine
    1 Mark
  21. 21.Give an example for substrate level phosphorylation
    1 Mark
  22. 22.Define epimerism
    1 Mark

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