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KUHS MBBS Biochemistry Previous Question Paper - November 2023 (115001 2019 Scheme)

115001Kerala University of Health Sciences · Biochemistry · 2023 · November · 2019 Scheme

Questions (22)

  1. 1.A 2-year-old child presented with complaints of on and off vomiting and lethargy for past two months. On examination child had a massive liver enlargement. Blood investigation reports were as follows: Blood sugar: 50mg%, Uric acid:10mg%, lactic acid:15mg%, Total cholesterol:300mg%. Liver biopsy demonstrated the mosaic pattern of enlarged hepatocytes, exhibiting abundant clear cytoplasm containing glycogen and lipid vacuoles. a) What is the diagnosis b) Name other glycogen storage disorders c) Explain how glycogen is metabolized in the body d) Explain the hormonal regulation of glycogen metabolism
    15 Marks
  2. 2.a) Define and classify enzymes giving one example each. b) Enumerate the factors affecting enzyme activity c) Describe the different types of enzyme inhibition with appropriate examples
    15 Marks
  3. 3.Describe the denovosynthesis of fatty acid. Add a note its regulation
    8 Marks
  4. 4.Describe the steps of catabolism of phenyl alanine and tyrosine. Add a note on inborn errors associated with them
    8 Marks
  5. 5.Outline the pathway of heme synthesis. Mention its regulation
    8 Marks
  6. 6.Define oxidative phosphorylation. Explain the chemiosmotic theory
    8 Marks
  7. 7.Explain how proteins are digested and absorbed in the body
    8 Marks
  8. 8.Protein energy malnutrition
    4 Marks
  9. 9.Mitochondria
    4 Marks
  10. 10.Explain the transport of dietary lipids from intestine
    4 Marks
  11. 11.Biochemical functions of vitamin A
    4 Marks
  12. 12.Folate trap Give Precise Answers
    4 Marks
  13. 13.NADPH generating steps in HMP shunt pathway
    1 Mark
  14. 14.Name the neurotransmitters formed from Tryptophan
    1 Mark
  15. 15.False positive benedict’s test
    1 Mark
  16. 16.Reference interval of following in plasma a) urea b) creatinine
    1 Mark
  17. 17.Define Mutarotation
    1 Mark
  18. 18.Enzyme defect in a) Maple Syrup Urine Disease b) Hereditary Fructose Intolerance
    1 Mark
  19. 19.Regulatory enzyme in cholesterol synthesis
    1 Mark
  20. 20.Name two enzymes that require pyridoxine as coenzyme
    1 Mark
  21. 21.Name ketone bodies
    1 Mark
  22. 22.Mention two semi essential amino acids
    1 Mark

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