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KUHS MBBS Biochemistry Previous Question Paper - January 2024 (115001 2019 Scheme)

115001Kerala University of Health Sciences · Biochemistry · 2024 · January · 2019 Scheme

Questions (22)

  1. 1.A 2-year-old child presented with liver enlargement and complaints of weakness, sweating and pallor which disappeared on eating food. Mother revealed that milestones were delayed. On investigation, blood glucose: 50 mg/dl, uric acid: 10 mg/dL, lactic acid: 15 mg/dL, cholesterol: 300 mg/dL, and presence of ketone bodies. a) What is the likely diagnosis b) Name the enzyme defect c) Discuss the pathways that lead to elevated levels of uric acid, lactic acid, and cholesterol d) Discuss the reason for liver enlargement e) Give the normal reference range for serum cholesterol and Fasting Blood glucose
    15 Marks
  2. 2.Discuss vitamin D under the following headings a) source b) daily requirements c) metabolism d) biochemical functions e) deficiency manifestations
    15 Marks
  3. 3.Explain the steps of β-oxidation of palmitic acid, giving energetics.
    8 Marks
  4. 4.Describe the steps by which catecholamines are synthesized. Outline the pathway of their degradation.
    8 Marks
  5. 5.How are dietary triglycerides absorbed and transported in plasma. Briefly explain the transport of dietary triglyceride from intestine to liver.
    8 Marks
  6. 6.What are the different types of enzyme inhibition. Explain with suitable examples.
    8 Marks
  7. 7.Discuss the biochemical alterations seen in blood and urine in different types of jaundice.
    8 Marks
  8. 8.Transamination
    4 Marks
  9. 9.Fluid mosaic model
    4 Marks
  10. 10.Dietary fiber
    4 Marks
  11. 11.Homocystinuria
    4 Marks
  12. 12.Chemiosmotic theory
    4 Marks
  13. 13.Why is heat coagulation irreversible
    1 Mark
  14. 14.Sucrose is a non-reducing sugar. Why
    1 Mark
  15. 15.Give two examples of high energy compounds
    1 Mark
  16. 16.Differentiate between cis and trans fatty acids
    1 Mark
  17. 17.Which tissues prefer anaerobic glycolysis
    1 Mark
  18. 18.Name the neuro transmitters formed from tryptophan
    1 Mark
  19. 19.Name the limiting amino acids in (a) Pulses (b) Cereals
    1 Mark
  20. 20.Homogentisic acid is excreted in urine in _________
    1 Mark
  21. 21.Name the enzyme defect in acute intermittent porphyria
    1 Mark
  22. 22.Newborns, especially premature infants, have relative vitamin K deficiency. Why
    1 Mark

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