KUHS MBBS Biochemistry Previous Question Paper - August 2021 (116001 2019 Scheme)

116001Kerala University of Health Sciences · Biochemistry · 2021 · August · 2019 Scheme

Questions (22)

1.A 45-year-old male patient reported to orthopedics outpatient department on Monday morning with pain and swelling of first metatarsophalangeal joint of right foot. He had consumed alcoholic drinks heavily on Saturday night. On examination the first metatarsophalangeal joint of right foot was warm, swollen and tender. • What is your diagnosis • What are the causes of this disorder • What are the investigations to confirm this disorder • What are the biochemical basis of management of this condition.
15 Marks
2.Write the definition, steps and inhibitors of transcription.
15 Marks
3.Principles and application of ELISA
8 Marks
4.Define metabolic acidosis. What are the characteristic features and causes of metabolic acidosis. Mention the compensatory mechanisms.
8 Marks
5.Enumerate the applications of recombinant DNA technology. Add a note on vectors
8 Marks
6.Describe the structure and functions of immunoglobulins
8 Marks
7.Mention the biochemical functions of calcium and describe the blood calcium homeostasis
8 Marks
8.Role of cytokines in immunity
4 Marks
9.Define mutations. Describe the causes of mutation
4 Marks
10.Hormones as tumor markers
4 Marks
11.Explain the absorption of iron
4 Marks
12.Explain the Watson and crick model of DNA
4 Marks
13.Rf value
1 Mark
14.Mention any two applications of PCR
1 Mark
15.Mention the enzyme deficient in Lesch Nyhan syndrome
1 Mark
16.Name two post translational modifications.
1 Mark
17.Name any two zinc containing enzymes
1 Mark
18.Name the RNA with catalytic activity
1 Mark
19.Two causes of respiratory acidosis
1 Mark
20.Name two characteristics of Genetic Code.
1 Mark
21.Give biological reference range for serum sodium
1 Mark
22.Bence – Jones proteins
1 Mark

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