KUHS MBBS Biochemistry Previous Question Paper - May 2023 (116001 2019 Scheme)

116001Kerala University of Health Sciences · Biochemistry · 2023 · May · 2019 Scheme

Questions (22)

1.42-year-old obese lady presented with intolerance to fatty foods and pain in right abdominal region. On examination, her eyes were yellowish; stools had clay-colored appearance. Her investigations revealed the following. Serum bilirubin -18 mg/dl Direct bilirubin-17 mg/dl AST-35 IU/L ALT-40 IU/L ALP-400 IU/L a) What is the probable diagnosis b) What is the normal serum Bilirubin level c) Describe the catabolism of Heme. d) What is the biochemical basis of clay colored stools e) What will be the probable urinary findings in this patient
15 Marks
2.Structure, types and functions of immunoglobulins.
15 Marks
3.Normal serum calcium and its regulation
8 Marks
4.What are the causes, biochemical findings and compensatory mechanisms in metabolic acidosis.
8 Marks
5.Phase I detoxification reaction.
8 Marks
6.Absorption, transport and storage of iron
8 Marks
7.What is the role of buffers in regulating blood pH
8 Marks
8.List the blot/blotting techniques and the applications of each type.
4 Marks
9.Keratin.
4 Marks
10.Outline the pathway of purine catabolism.
4 Marks
11.Micro arrays.
4 Marks
12.Role of oxidative stress in pathogenesis of cancer.
4 Marks
13.Enzyme defect in Lesch – Nyhan syndrome.
1 Mark
14.Functions of iodine.
1 Mark
15.A patient presented with excretion of urine more than 20 litres per day. Specific gravity of his urine sample was 1.002. What is your diagnosis.
1 Mark
16.Degeneracy of genetic code.
1 Mark
17.What is the role of Telomerase enzyme.
1 Mark
18.Fastest moving plasma protein in electrophoresis is---------
1 Mark
19.Two copper containing enzymes.
1 Mark
20.Name four oncogenes.
1 Mark
21.One example for Prion disease.
1 Mark
22.Reference interval of serum sodium and potassium.
1 Mark

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