NTRUHS MBBS Biochemistry August 2024 (M102A030 Regular)

M102A030Dr. NTR University of Health Sciences · Biochemistry · 2024 · August · Regular

Questions (12)

1.A 30-year-old man, a Strict vegetarian who does not consume even dairy products, came to the hospital with complaints of weakness, pallor, loss of sensation in the extremities, and mental confusion. On investigation, his Hb levels were found to be 7g/dl. His blood picture showed large abnormal and immature RBC. On urine examination, large amounts of methylmalonic acid a) What is your probable diagnosis? And interpret the case. b) What are the deficiency manifestations of Vitamin B12? And explain them. c) Write about absorption and transport of Vitamin B12? d) What are the biochemical functions of VitB12? e) Add a note on the metabolic link between VitB12 and folic acid.
15 Marks
2.Describe the classification and structural organization of lipoproteins? Write in detail about the transportation of lipids in the body. Add a note on disorders of lipoproteins.
15 Marks
3.Write about the glycemic index and its significance.
5 Marks
4.Describe the diagnostic importance of serum enzymes in various diseases.
5 Marks
5.Explain detoxification by conjugation with four examples.
5 Marks
6.Write about the formation and absorption of amino acids.
5 Marks
7.Write about the mechanisms of amino acid absorption.
5 Marks
8.What are enzymes involved in biological oxidation? Explain their functions with examples.
5 Marks
9.Describe the uronic acid pathway and its clinical significance.
5 Marks
10.Metabolic changes in starvation.
5 Marks
11.Describe the tests to assess glomerular function.
5 Marks
12.Write about the sources and generation of reactive oxygen species.
5 Marks

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