NTRUHS MBBS Biochemistry March 2024 (M102A030 Regular)

M102A030Dr. NTR University of Health Sciences · Biochemistry · 2024 · March · Regular

Questions (12)

1.A 40-year-old man is brought to the hospital in a comatose state. On examination, he was found to be dehydrated and toxic with a characteristic breathing pattern with sweet smell. He was admitted and investigated. Following are his lab investigations: RBS :380 mg/dl S. HCO3: 15 mEq/L S. Ketones: 80mg/dl pH: 7.25 www.FirstRanker Urinary Benedicts test: ++++ Urinary Rothera's test: Positive Answer the following: a) What is your diagnosis? b) What are the favourable points for your diagnosis? c) Explain the metabolism of Ketone Bodies? d) Write about the hormonal regulation of blood glucose. e) What are the differences between types of Diabetes Mellitus?
15 Marks
2.Define the lipoproteins and classify them. Explain the LDL metabolism. Write about Atherosclerosis.
15 Marks
3.Describe the types of PEM (Protein Energy Malnutrition).
5 Marks
4.Define BMR. What is its normal value? What are the factors affecting BMR?
5 Marks
5.HMP shunt and its significance.
5 Marks
6.What are isoenzymes? Write about cardiac isoenzymes.
5 Marks
7.Enumerate the types of Heteropolysaccharides and write their biochemical significance.
5 Marks
8.What are antioxidants? Give two examples of: Antioxidant enzymes Antioxidant vitamins Antioxidant minerals
5 Marks
9.Write in detail about ETC. Add a note on.its inhibition and uncouplers of oxidative phosphorylation.
5 Marks
10.What are the factors affecting enzyme activity? Add a note on competitive inhibition.
5 Marks
11.What is clearance? What are the different types of clearance tests you know and their significance?
5 Marks
12.Describe the steps of heme synthesis. Add a note on AIP (Acute Intermittent Porphyria).
5 Marks

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