apyqace

RGUHS MBBS Biochemistry October 2025 (1024 CBME)

1024Rajiv Gandhi University of Health Sciences · Biochemistry · 2025 · October · CBME

Questions (30)

  1. 1.A 5 year old child was brought to the hospital with complaints of slow growth and pain in bones. On examination, he was anaemic, had frontal bossing, bowing of legs and swelling of costochondral junction. Following are his laboratory findings: Serum calcium: 8.6 mg/ dL, Serum phosphorous: 2.6 mg/dL, and Serum alkaline phosphatase: 700 U/L. a) Mention the vitamin deficiency in this child. b) Describe the Sources, Formation, Biochemical functions and recommended dietary allowance (RDA) of above vitamin.
    10 Marks
  2. 2.Explain the factors affecting enzyme activity. Mention two therapeutic importance of enzymes.
    10 Marks
  3. 3.A 44 year old male presented with chest pain. Family history shows that his father died of a heart attack at the age of 46 years, and his elder brother also had a heart attack at the same age. The patient reports that he gets chest pain occasionally with ambulation and is not able to climb stairs without significant chest pain and shortness of breath. His Serum cholesterol was 440.0 mg/dl. a) What is the probable cause for hyperlipidemia in this case? b) Name two hyperlipoproteinemias along with their biochemical defect. c) Mention one lipid lowering drug along with its mechanism of action
    5 Marks
  4. 4.A 25 year old female during her second pregnancy had a glucose tolerance test and her results are as follows. Fasting glucose level: 125 mg/dL, first hour glucose level: 210 mg/dL, and second hour glucose level: 170 mg/dL. a) Interpret the above laboratory findings. b) Name the types of diabetes mellitus. c) Mention the biochemical tests used to monitor diabetes and its complications.
    5 Marks
  5. 5.Define Basal metabolic rate. Discuss the factors affecting it.
    5 Marks
  6. 6.Classify phospholipids. Write their functions.
    5 Marks
  7. 7.Describe electron transport chain. Mention two inhibitors of electron transport chain.
    5 Marks
  8. 8.List five subcellular organelles and enumerate their functions.
    5 Marks
  9. 9.Write the causes and laboratory findings in Iron deficiency anemia.
    5 Marks
  10. 10.Define and Classify carbohydrates with examples.
    5 Marks
  11. 11.Mention the mechanisms involved in maintenance of blood pH.
    3 Marks
  12. 12.List the hormones involved in homeostasis of calcium.
    3 Marks
  13. 13.What is hypernatremia? Mention two clinical conditions associated with hypernatremia.
    3 Marks
  14. 14.Mention the cause and clinical features of scurvy.
    3 Marks
  15. 15.Enumerate three coenzymes with their functions.
    3 Marks
  16. 16.HDL – cholesterol is called good cholesterol - justify.
    3 Marks
  17. 17.List the biologically important Products obtained from cholesterol.
    3 Marks
  18. 18.What is Metabolic acidosis? Mention two causes for it.
    3 Marks
  19. 19.Mention three proteins present in extracellular matrix.
    3 Marks
  20. 20.Mention the key enzymes catalyzing irreversible steps in gluconeogenesis.
    3 Marks
  21. 21.The end product of glycolysis in erythrocytes is A. NADPH B. Lactate C. Pyruvate D. Carbon dioxide
    1 Mark
  22. 22.Reference range for total serum calcium is A. 0.6-1.4 mg/dl B. 9-11 mg/dl C. 15-40 mg/dl D. 70-110 mg/dl
    1 Mark
  23. 23.Glucose level in plasma is increased by A. Gluconeogenesis B. Glycolysis C. Glycogen synthesis D. Glycosuria
    1 Mark
  24. 24.Koilonychia or spoon nail is seen in A. Iron deficiency anaemia B. Megaloblastic anaemia C. Scurvy D. Rickets
    1 Mark
  25. 25.Ketone bodies are mainly produced in A. Brain B. Liver C. Erythrocytes D. Skeletal muscles
    1 Mark
  26. 26.Calories generated per gram of fat is A. 4 kcal B. 5 kcal C. 8 kcal D. 9 kcal
    1 Mark
  27. 27.Methionine is a limiting amino acid in A. Cereals B. Maize and corn C. Pulses D. Tapioca
    1 Mark
  28. 28.Administration of diuretics cause loss of potassium, which may lead to A. Respiratory acidosis B. Respiratory alkalosis C. Metabolic acidosis D. Metabolic alkalosis
    1 Mark
  29. 29.When pH falls by 1 unit, hydrogen ion concentration A. Remains same B. Increases by 2 times C. Increases by 7 times D. Increases by 10 times
    1 Mark
  30. 30.Major intracellular cation is A. Magnesium B. Potassium C. Sodium D. Calcium
    1 Mark

More from Biochemistry

Biochemistry question papers & analysis

Previous-year question paper.More papers →Report an issue
Question content is not available for printing. View it at pyqace.com