RGUHS MBBS Physiology January 2026 (1022 CBME)

1022Rajiv Gandhi University of Health Sciences · Physiology · 2026 · January · CBME

Questions (30)

  1. 1.Describe intrinsic pathway of coagulation. Classify anticoagulants. Explain the action of Heparin as an anticoagulant. Add a note on Christmas disease
    10 Marks
  2. 2.A patient with h/o severe vomiting and diarrhea since 2 days was brought to the hospital in unconscious state. On examination, pulse rate was 104/min and thready pulse, skin as pale, BP was 80/56 mmHg. a) What is your diagnosis? b) Define and classify Shock c) Describe the stages of Shock
    10 Marks
  3. 3.Classify body fluid compartments. Describe measurement of any one compartment
    5 Marks
  4. 4.Explain the mechanism of cell mediated immunity.
    5 Marks
  5. 5.Name the different types of heart blocks and explain in brief.
    5 Marks
  6. 6.Describe the role of peripheral chemoreceptors in regulation of respiration
    5 Marks
  7. 7.Explain micturition reflex. What is the reason for plateau phase noted in cystometrogram?
    5 Marks
  8. 8.A patient came with a h/o pain abdomen, loss of appetite, fatigability, yellowish discoloration of skin and passing of clay colored stools. a) What is your diagnosis? b) What is the reason or yellowish discoloration of skin and clay colored stools? c) Enlist the functions of bile salts
    5 Marks
  9. 9.Describe the phases of cardiac action potential with ionic basis
    5 Marks
  10. 10.Explain the basis for physiological changes noted at high altitude
    5 Marks
  11. 11.Enlist the complications of hemolytic disease of newborn.
    3 Marks
  12. 12.Explain Reynold’s number and its significance.
    3 Marks
  13. 13.Why intrapleural pressure is negative? Write its normal range.
    3 Marks
  14. 14.What is Achalasia cardia?
    3 Marks
  15. 15.State the features of stagnant hypoxia
    3 Marks
  16. 16.Enlist the actions of Secretin
    3 Marks
  17. 17.What is aldosterone escape?
    3 Marks
  18. 18.What is Asphyxia? Name a cause for it.
    3 Marks
  19. 19.Enlist the factors affecting glomerular filtration rate.
    3 Marks
  20. 20.What are the components and functions of Enteric nervous system?
    3 Marks
  21. 21.21 Obligatory urine volume, considering a maximum urine osmolality of 1200mOsm/L is A. 0.5 L/day B. 1 L/day C. 1.5 L/day D. 2 L/day
    1 Mark
  22. 22.22 Which is the major site of reabsorption of bicarbonate? A. Proximal tubule B. Descending limb of loop of Henle C. Ascending limb of loop of Henle D. Distal tubule
    1 Mark
  23. 23.23 Which neurotransmitter is primarily involved in stimulating acid secretion during the cephalic phase? A. Acetylcholine B. Dopamine C. Serotonin D. Histamine
    1 Mark
  24. 24.Which of the following gases is used to measure the diffusing capacity of the lungs? A. Nitrogen B. Argon C. Carbon monoxide D. Carbon dioxide
    1 Mark
  25. 25.Which of the RBC indices best differentiates megaloblastic anemia from iron deficiency anemia? A. Mean corpuscular volume B. Mean corpuscular hemoglobin C. Mean corpuscular hemoglobin concentration D. Mean corpuscular width
    1 Mark
  26. 26.21 What is the normal level of albumin in the blood? A. 0.3-0.7 g/dL B. 3.5-5.5 g/dL C. 1.5-4.5 g/dL D. 10-50 g/dL
    1 Mark
  27. 27.21 Which of the following durations is normal for the P-R interval? A. 0.04 to 0.08 s B. 0.08 to 0.16 s C. 0.12 to 0.2 s D. 0.16 to 0.24 s
    1 Mark
  28. 28.Which of the following statements is true of the conducting system of the heart? A. Conduction is slower than through cardiac muscle B. Prevents delay of impulse from atria to ventricle C. Excites almost all ventricular muscles together D. Prevents the heart from beating fast
    1 Mark
  29. 29.Which of the following causes increase in both GFR and renal plasma flow? A. Increased plasma colloid osmotic pressure B. Dilatation of afferent arterioles C. Constriction of afferent arterioles D. Increased tubular pressure
    1 Mark
  30. 30.Macula densa in kidney is located in relation to A. Proximal Convoluted Tubule B. Distal Convoluted Tubule C. Afferent arteriole D. Efferent arteriole
    1 Mark

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