RGUHS MBBS Physiology January 2026 (1023 CBME)

1023Rajiv Gandhi University of Health Sciences · Physiology · 2026 · January · CBME

Questions (30)

  1. 1.What is the normal plasma calcium level? Describe the physiological actions of hormones in calcium homeostasis? Add a note on Hypocalcemic tetany?
    10 Marks
  2. 2.Define muscle tone. With the help of a neat labelled diagram of muscle spindle, describe regulation of muscle length?
    10 Marks
  3. 3.1. A 50 year old bus driver is not able to perform his professional work. He complains of tremor during rest and not able to initiate a movement. He takes short quick steps while walking. Answer the following questions: a) What is your probable diagnosis? b) Explain the pathophysiology underlying this condition c) What is the most commonly used treatment modality?
    5 Marks
  4. 4.Describe the mechanism and regulation of biosynthesis of thyroid hormones.
    5 Marks
  5. 5.Describe the functions of cerebellum.
    5 Marks
  6. 6.Define accommodation in the eye. Trace the pathway and explain the mechanism of accommodation reflex.
    5 Marks
  7. 7.Explain the stages and regulation of spermatogenesis
    5 Marks
  8. 8.Describe the molecular basis of skeletal muscle contraction.
    5 Marks
  9. 9.Name the hormones influencing growth. Describe the actions of Growth hormone on somatic growth.
    5 Marks
  10. 10.What is synaptic inhibition? What is its ionic basis? What are the types of synaptic inhibition?
    5 Marks
  11. 11.Children suffering from Cretinism have short stature and mental retardation .why?
    3 Marks
  12. 12.List the differences between alpha and beta EEG waves. Add a note on alpha block.
    3 Marks
  13. 13.Acupuncture reduces pain. What is the physiological basis?
    3 Marks
  14. 14.Draw a labelled diagram showing the origin, course and termination of corticospinal pathway
    3 Marks
  15. 15.Enumerate the functions of middle ear.
    3 Marks
  16. 16.Explain the basis of phenomenon of phantom limb in amputated individuals
    3 Marks
  17. 17.Explain the double Bohr effect across placenta?
    3 Marks
  18. 18.Explain any three functions of blood testis barrier
    3 Marks
  19. 19.What is the importance of hormones in gender differentiation?
    3 Marks
  20. 20.Describe the hormonal control of follicular phase of ovarian cycle
    3 Marks
  21. 21.The amount of tension actually generated by the cross bridge movement of muscle is called A. Total tension B. Passive tension C. Active tension D. None of the above
    1 Mark
  22. 22.Tropomyosin A. Helps in fusion of troponin and myosin B. Causes calcium release C. Slides over myosin D. Prevents attachment of actin and myosin
    1 Mark
  23. 23.Motor aphasia refers to defect in A. Peripheral speech apparatus B. Verbal expression C. Auditory comprehension D. Verbal comprehension
    1 Mark
  24. 24.Which of the following is the major neurotransmitter in nigro-striatal pathway A. Dopamine B. Noradrenaline C. Acetyl choline D. Serotonin
    1 Mark
  25. 25.Which of the following sensations are transmitted by the dorsal column pathway A. Fine touch, proprioception B. Pain C. Temperature D. Crude touch
    1 Mark
  26. 26.The depolarization of hair cell is due to the influx of A. Sodium ion B. Potassium ion C. Calcium ion D. Magnesium ion
    1 Mark
  27. 27.Bitemporal hemianopia occurs when the lesion is present in the A. Right optic nerve B. Temporal retina C. Optic chiasma D. Left geniculocalcarine tract
    1 Mark
  28. 28.Which nucleus of thalamus controls visual functions? A. Medial geniculate body B. Lateral geniculate body C. Pulvinar D. Anterior thalamus
    1 Mark
  29. 29.The dorsal root of spinal cord is sensory and ventral root is motor. This is called A. Weber- Fechner law B. Muller’s doctrine of nerve energy C. Bell – Magendie law D. Law of projection
    1 Mark
  30. 30.FSH acts on which of the following A. Granulosa cell B. Theca interna C. Endometrium D. Myometrium A.
    1 Mark

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