apyqace

RGUHS MBBS Physiology January 2026 (5503 CBME)

5503Rajiv Gandhi University of Health Sciences · Physiology · 2026 · January · CBME

Questions (27)

  1. 1.Define cardiac output. Give the formula for cardiac index & mention the normal value. Describe the various factors maintaining cardiac output.
    3 Marks
  2. 2.Why erythroblastosis fetalis is common in 2nd born infant born to a Rh negative mother?
    3 Marks
  3. 3.Explain why there is Increased incidence of tuberculosis in the apex of the lung.
    3 Marks
  4. 4.Explain the physiological basis for renal splay.
    3 Marks
  5. 5.Describe the basis for triple response.
    3 Marks
  6. 6.Why there is alternate apnoea and hyperpnea in cheyne stokes breathing?
    5 Marks
  7. 7.Explain the pathophysiology of peptic ulcer disease. Add a note on treatment of peptic ulcer disease.
    5 Marks
  8. 8.Define Blood pressure. Explain the role of CNS ischemic response in regulating blood pressure.
    5 Marks
  9. 9.Describe the complications of blood transfusion.
    5 Marks
  10. 10.Explain the steps of phagocytosis.
    5 Marks
  11. 11.Describe briefly the mechanical events of cardiac cycle.
    5 Marks
  12. 12.Describe the different steps of erythropoiesis and its regulation.
    5 Marks
  13. 13.Explain Oxygen Dissociation Curve with a neat labelled diagram. Mention the factor which shifts the curve to right.
    5 Marks
  14. 14.Describe the counter current multiplier in the kidney.
    5 Marks
  15. 15.Explain the types of small intestinal movements.
    5 Marks
  16. 16.Describe chemical regulation of respiration.
    5 Marks
  17. 17.What are the different ways illness can impact a patient ‘s life beyond physical symptoms?
    5 Marks
  18. 18.A woman aged 30 years complains of general fatigue, breathlessness on exertion, giddiness and palpitation. On examination, patient had pallor of skin and mucous membrane, glossitis and koilonychia. Investigations revealed: Hemoglobin: 6gm/dl, RBC count: 3 million cells/cu mm of blood, MCHC: 28%, MCV: 60 cumm3, Eosinophilia. Stool examination: Hookworm ova present 18 (i) Identify the condition A. Bronchial Asthma B. Iron deficiency Anemia C. Jaundice D. Aplastic Anemia 18 (ii) What type of blood picture is seen in the above condition? A. Normocytic normochromic B. Microcytic normochromic C. Microcytic hypochromic D. Macrocytic normochromic
  19. 19.A 40-year old businessmen visit the OPD with chief complaints of severe nausea and pain in epigastric region which used to increase after taking food. Past history reveals frequent intake of pain killers for headache. The ECG recording was normal 19 (i) What is the probable condition? A. Pleuritis B. Chronic gastritis C. Pneumonia D. Myocardial Infraction 19 (ii) Which cells secrets HCl? A. Pareital cells B. Chief cells C. D- cells D. Alpha cells
  20. 20.A 56-year old man with a history of smoking presents to his primary care physician with shortness of breath and cough for several days. His symptoms began 3 days ago with rhinorrhea. He reports a chronic morning cough productive of white sputum, which has increased over the past 2 days 20 (i) What is the probable condition? A. COPD B. Pneumoconiosis C. Interstitial lung disease D. Pericarditis 20 (ii) What is the common method used to assess the severity of the above condition? A. Pulmonary function Test B. Blood pressure monitoring C. Heart rate variability D. ECHO
  21. 21.A duty nurse has mistakenly started A+ blood transfusion to a patient with B+ group which she realizes after patient complained of uneasiness and feverish feeling. 21 (i) Identify the condition A. Rh incompatibility B. ABO incompatibility C. Jaundice D. Aplastic Anemia 21 (ii) Blood groups were discovered by A. William Harvey B. Louis Pasteur C. Duffy D. Karl Landsteiner
  22. 22.A 65-year old male presents to the clinic with complaints of dizziness and light headedness, particularly when standing up. His heart rate is irregular and on examination, it is found to be slow. An ECG shows an abnormally prolonged PR interval. 22 (i) This finding is most consistent with? A. First degree AV Block B. Second Degree AV Block, Mobitz Type I C. Second Degree AV Block, Mobitz Type II D. Third Degree AV Block 22 (ii) What could happen if there was no AV nodal delay: A. The ventricles would contract before the atria have a chance to empty B. The heart rate would be slower C. The blood would not be pumped efficiently D. Both A and C
  23. 23.A 50-year male visited OPD with complaints of weight loss, weakness and fatiguability for more than 6 months. On clinical examination he had marked splenomegaly, mild hepatomegaly. Total leucocyte count (TLC) was 1.2 lakhs per cubic mm of blood. Examination of peripheral blood smear revealed more number of myelocytes and metamyelocytes with many neutrophils. 23 (i) What is the most probable condition? A. Hepatitis B. Leukemia C. Gilbert’s Syndrome D. Hemolytic Jaundice 23 (ii) Eosinophilia is seen in all EXPECT A. Bronchial asthma B. Worm infestation C. Cushing’s syndrome D. Urticaria
  24. 24.A patient having uncontrolled diabetes with urinary tract infection not responding to conventional antibiotic therapy was brought to the hospital in an unconscious state. 24 (i) What is the probable condition? A. Anaphylactic shock B. Septic shock C. Hypovolemic shock D. Obstructive shock 24 (ii) All are the short term regulation of blood pressure EXPECT: A. Baroreceptor reflex B. Chemical regulation C. Renal Mechanism D. CNS ischemic response
  25. 25.A 65-year old male was brought to the hospital with following features. He was a hypertensive and a diabetic on irregular treatment. He had signs and symptoms of pedal edema, fatigue, vomiting and loss of appetite. On examination, his urea and creatinine levels were very high. 25 (i) What is the probable diagnosis? A. Urinary tract infection B. Polycystic kidney C. Renal failure D. Neurogenic bladder 25 (ii) The following is an abnormal constituents of urine A. Urea B. Uric acid C. Creatinine D. Proteins
  26. 26.A 28-year old diabetic mother delivered the child through cesarean section at 32 weeks of gestation. The newborn baby had difficulty in breathing. The respiratory rate was 80 breaths/min. There was a grunting sound during expiration. The baby also had central cyanosis. 26 (i) What is the possible condition? A. Hyaline membrane disease B. Congenital heart disease C. Bacterial Pneumonia D. Pneumothorax 26 (ii) Pulmonary surfactant is produced by A. Type I alveolar cells B. Type II alveolar cells C. Mast cells D. APUD cells
  27. 27.A 65-year old male had recent stroke presents with urinary frequency, urgency and dribbling. He also reports difficulty in initiating urination and feels he can’t fully empty his bladder. The bladder capacity is decreased and the muscle of bladder is hypertrophied 27 (i) what is the probable diagnosis? A. Urinary tract infection B. Automatic bladder C. Neurogenic bladder D. Bladder tumor 27 (ii) Voluntary control of bladder is possible because of contraction of A. Abdominal muscles B. Perineal muscles and external sphincter C. Pelvic floor muscles D. Detrusor muscles

More from Physiology

Physiology question papers & analysis

Previous-year question paper.More papers →Report an issue
Question content is not available for printing. View it at pyqace.com