KNRUHS MBBS Physiology September 2025 (MB2019105 Regular)

MB2019105Kaloji Narayana Rao University of Health Sciences · Physiology · 2025 · September · Regular

Questions (25)

1.Hering Breuer Reflex protects lung from a) Circulating Toxins b) Circulating Phagocytes c) Overinflation d) Under Ventilation
1 Mark
2.Which of the following organs has the greatest blood flow per 100g of tissue? a) Brain b) Skin c) Kidney d) Liver
1 Mark
3.The most appropriate index of left ventricular afterload is a) Systolic arterial pressure b) Mean arterial pressure c) Systemic vascular resistance d) Left ventricular systolic pressure
1 Mark
4.Major source of ammonia production in renal tubular cell is by a) Deamination of glutamine b) Deamination of glutamic acid c) Deamination of other amino acids, glycine, asparagine. alanine d) Comes directly from arterial blood
1 Mark
5.Cholerectics are the substances which causes a) Contraction of gall bladder b) Increase biliary secretion from liver c) Neutralization of acid from stomach d) Solubility of fats in micelles
1 Mark
6.First heart sound (HS1): a) Marks the onset of ventricular systole b) Caused by the closure of semilunar valves c) Best heard over aortic and pulmonary areas d) Characterized by high pitch and sharp sound
1 Mark
7.The renal "countercurrent" mechanism is dependent upon the anatomic relationship between: a) The distal tubule and the macula densa b) The loop of Henle and the macula densa c) The loop of Henle and the vasa recta d) The glomerulus and the afferent and efferent arterioles
1 Mark
8.The adhesion of platelets to subendothelial collagen is impaired in the absence of: a) Von Willebrand factor b) Plasmin c) Heparin d) Antithrombin III
1 Mark
9.The function of axonemal dynein is? a) Moves particles to the 'minus' end of microtubule. b) Binds to actin and produce motion by bending their neck region. c) Responsible for the beating of flagella and cilia. d) Moves particles towards 'plus' end of microtubule.
1 Mark
10.Cholesterol content of a cell membrane influences which of the following characteristics of biological membrane a) Ion permeability b) Fluidity c) Glycosylation d) Hydrophobicity
1 Mark
11.An elderly male came to hospital with history of chest pain and breathing difficulty on and off for 2 days. His ECG showed ST segment depression and echocardiography showed that his stroke volume in <50%. a) Identify the condition. b) Define stroke volume, cardiac output and cardiac index with their normal value. c) Describe the factors regulating cardiac output. d) Define Fick’s principle. Mention the methods to measure cardiac output.
15 Marks
12.A young male went for trekking 2500m above sea level. On arrival to his stay, he complained of breathlessness. His Spo2 was 70% in room air. a) Identify the condition. b) Describe the classification and patho physiology of Hypoxia c) Enumerate the treatment for the types of Hypoxia d) Discuss on Hyperbaric O2 therapy.
15 Marks
13.Describe the mechanism of HCL secretion in stomach
6 Marks
14.Name the different body fluid compartments. Give the composition of extracellular and intracellular fluids. Mention the methods to measure ECF.
6 Marks
15.Describe Defecation reflex.
6 Marks
16.Classify leukocytes. Describe the stages of leucopoiesis.
6 Marks
17.Define haemostasis. Describe the extrinsic mechanism of coagulation.
6 Marks
18.Enumerate the measures that strengthen the doctor patient relationship.
6 Marks
19.Briefly explain water reabsorption by Kidney.
6 Marks
20.Draw a neat labelled diagram of nerve action potential mentioning reasons for each phase.
3 Marks
21.List functions of plasma proteins
3 Marks
22.Draw a neat labelled diagram of Juxtaglomerular apparatus.
3 Marks
23.Define uniport, symport and antiport with examples.
3 Marks
24.Define urea clearance. How is it calculated. Name any other 2 substances used to measure renal clearance.
3 Marks
25.Write the significance of Dietary fibres.
3 Marks

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